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STRidER: Saudi Arabia

Study statistics

Loci
17 Autosomal STRs
Allele type
Unknown
Sample size
500
Population
Unknown
Location
Saudi Arabia
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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D11S2368 500 - - - - - - - -
D13S325 500 - - - - - - - -
D14S1434 500 - - - - - - - -
D15S659 500 - - - - - - - -
D17S1301 500 - - - - - - - -
D18S1364 500 - - - - - - - -
D19S253 500 - - - - - - - -
D20S482 500 - - - - - - - -
D21S2055 500 - - - - - - - -
D22GATA198B05 500 - - - - - - - -
D3S1744 500 - - - - - - - -
D4S2366 500 - - - - - - - -
D5S2800 500 - - - - - - - -
D6S474 500 - - - - - - - -
D7S3048 500 - - - - - - - -
D8S1132 500 - - - - - - - -
D9S1122 500 - - - - - - - -

Allele frequencies

D11S2368 D13S325 D14S1434 D15S659 D17S1301 D18S1364 D19S253 D20S482 D21S2055 D22GATA198B05 D3S1744 D4S2366 D5S2800 D6S474 D7S3048 D8S1132 D9S1122
6 0.001 0.004
7 0.003 0.222 0.001
8 0.018
9 0.001 0.006 0.001 0.009 0.01 0.299 0.008
10 0.29 0.037 0.042 0.018 0.004 0.107 0.001 0.054
11 0.036 0.222 0.292 0.001 0.147 0.007 0.172 0.237
11.2 0.001
12 0.018 0.163 0.449 0.045 0.353 0.039 0.004 0.001 0.243 0.405
13 0.261 0.059 0.188 0.247 0.16 0.222 0.008 0.106 0.021 0.002 0.256
13.1 0.001
14 0.001 0.384 0.037 0.023 0.142 0.061 0.477 0.01 0.117 0.066 0.238 0.345 0.031
15 0.002 0.006 0.207 0.005 0.185 0.007 0.186 0.011 0.079 0.005 0.003 0.244 0.003 0.007
16 0.016 0.004 0.004 0.18 0.126 0.001 0.052 0.131 0.133 0.002 0.001 0.214 0.003 0.016 0.001
16.1 0.082
17 0.048 0.012 0.061 0.043 0.003 0.188 0.34 0.239 0.143 0.068 0.138
17.1 0.013
18 0.143 0.045 0.021 0.143 0.099 0.167 0.28 0.039 0.091 0.211
18.1 0.013
19 0.241 0.167 0.003 0.062 0.244 0.096 0.006 0.012 0.061 0.2
19.1 0.108
20 0.266 0.308 0.006 0.153 0.045 0.025 0.075 0.124
20.1 0.01
21 0.206 0.231 0.11 0.012 0.106 0.105
22 0.059 0.141 0.044 0.002 0.003 0.086 0.106
23 0.016 0.071 0.001 0.005 0.165 0.186 0.069
24 0.002 0.017 0.026 0.019 0.181 0.023
25 0.001 0.131 0.098 0.004
26 0.121 0.037
26.3 0.002
27 0.014 0.006
27.3 0.001
28 0.012 0.001
29 0.056
30 0.032 0.001
31 0.041
32 0.102
33 0.124
34 0.07
35 0.034
36 0.008
37 0.002

Locus histograms

D11S2368

D13S325

D14S1434

D15S659

D17S1301

D18S1364

D19S253

D20S482

D21S2055

D22GATA198B05

D3S1744

D4S2366

D5S2800

D6S474

D7S3048

D8S1132

D9S1122