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STRidER: Vietnam

Study statistics

Loci
22 Autosomal STRs
Allele type
Unknown
Sample size
1000
Population
Unknown

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Bibliographic information

Date published
Nov. 7, 2024
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

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Normalized frequencies
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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 1000 - - - - - - - -
D10S1248 1000 - - - - - - - -
D12S391 1000 - - - - - - - -
D13S317 1000 - - - - - - - -
D16S539 1000 - - - - - - - -
D18S51 1000 - - - - - - - -
D19S433 1000 - - - - - - - -
D1S1656 1000 - - - - - - - -
D21S11 1000 - - - - - - - -
D22S1045 1000 - - - - - - - -
D2S1338 1000 - - - - - - - -
D2S441 1000 - - - - - - - -
D3S1358 1000 - - - - - - - -
D5S818 1000 - - - - - - - -
D7S820 1000 - - - - - - - -
D8S1179 1000 - - - - - - - -
FGA 1000 - - - - - - - -
Penta D 1000 - - - - - - - -
Penta E 1000 - - - - - - - -
TH01 1000 - - - - - - - -
TPOX 1000 - - - - - - - -
VWA 1000 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA Penta D Penta E TH01 TPOX VWA
5 0.0005 0.049 0.0005
5.2 0.0005
6 0.0005 0.1275
7 0.01 0.001 0.0415 0.008 0.0005 0.0365 0.006 0.3315 0.0005
7.3 0.0005
7.4 0.0005
8 0.0005 0.3105 0.0045 0.0005 0.002 0.165 0.0025 0.076 0.002 0.061 0.569
8.1 0.0005 0.0005
8.4 0.0005
9 0.037 0.1435 0.218 0.0005 0.016 0.001 0.002 0.0705 0.0655 0.0015 0.3175 0.012 0.3565 0.0995
9.1 0.0125 0.0105
9.2 0.0005
9.3 0.0495
10 0.215 0.0015 0.132 0.111 0.002 0.004 0.234 0.2375 0.16 0.1565 0.15 0.048 0.0715 0.0345 0.0005
10.1 0.001 0.001
11 0.2805 0.0015 0.215 0.2885 0.007 0.004 0.079 0.165 0.315 0.001 0.277 0.3515 0.137 0.126 0.261 0.0015 0.2735
11.1 0.0005 0.0015
11.2 0.0015 0.003
11.3 0.1085
12 0.3575 0.0625 0.15 0.2555 0.0565 0.0475 0.0445 0.0015 0.1715 0.0005 0.2235 0.2035 0.125 0.1415 0.1155 0.0005 0.021 0.0005
12.1 0.0005
12.2 0.005
12.3 0.003
13 0.0845 0.3225 0.0395 0.102 0.1395 0.245 0.086 0.0055 0.0095 0.002 0.1385 0.029 0.165 0.001 0.088 0.059 0.0015 0.0005
13.2 0.04
13.3 0.0005
14 0.012 0.262 0.0085 0.019 0.2005 0.2595 0.0815 0.03 0.0005 0.13 0.039 0.0085 0.004 0.1495 0.0425 0.0765 0.3055
14.1 0.0005
14.2 0.091
15 0.0025 0.23 0.013 0.0015 0.2095 0.0795 0.295 0.303 0.0105 0.2925 0.0005 0.166 0.0125 0.066 0.0225
15.1 0.0005
15.2 0.155 0.0005
15.3 0.004
16 0.0925 0.004 0.1635 0.0085 0.187 0.2395 0.025 0.001 0.365 0.0775 0.0015 0.0035 0.065 0.1415
16.2 0.0405
16.3 0.012
16.4 0.0005
17 0.021 0.0645 0.0765 0.001 0.077 0.2305 0.1005 0.237 0.0145 0.0015 0.0565 0.232
17.2 0.0045 0.0005
17.3 0.001 0.0845
17.4 0.002
18 0.0065 0.189 0.0425 0.0155 0.02 0.081 0.057 0.004 0.0195 0.0005 0.0565 0.192
18.2 0.0015
18.3 0.001 0.0205
18.4 0.0015
19 0.205 0.036 0.0055 0.0035 0.209 0.005 0.0005 0.0925 0.0005 0.0405 0.087
19.3 0.0005 0.002
20 0.185 0.021 0.0005 0.0005 0.1025 0.001 0.0525 0.0245 0.017
20.2 0.0005
21 0.1305 0.022 0.0515 0.143 0.024 0.001
21.2 0.012
22 0.105 0.0135 0.0005 0.0415 0.1925 0.0145
22.2 0.0105
23 0.0625 0.003 0.172 0.15 0.0105
23.2 0.0105
24 0.019 0.0045 0.148 0.137 0.003
24.2 0.0145
25 0.0155 0.0015 0.0595 0.0905 0.0035
25.2 0.0105
26 0.004 0.0015 0.007 0.036 0.001
26.2 0.0025
27 0.0005 0.0035 0.002 0.018
27.2 0.0005
28 0.0575 0.003
28.2 0.003
29 0.266
29.2 0.002
30 0.224
30.2 0.019
30.3 0.0015
31 0.0745
31.2 0.0855
32 0.0275
32.1 0.0005
32.2 0.157
33 0.005
33.2 0.0655
34 0.0015
34.2 0.0045
35.2 0.0005

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