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STRidER: Europe

Study statistics

Loci
28 Autosomal STRs
Allele type
Length-based alleles
Sample size
up to 10713
Population
Unknown

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Bibliographic information

Date published
Nov. 7, 2024
Data version
v3/R4
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online) a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

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Normalized frequencies
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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 6030 - - - - - - - -
D10S1248 10712 - - - - - - - -
D10S2325 2125 - - - - - - - -
D12S391 10713 - - - - - - - -
D13S317 6030 - - - - - - - -
D16S539 10712 - - - - - - - -
D18S51 10710 - - - - - - - -
D19S433 10712 - - - - - - - -
D1S1656 10713 - - - - - - - -
D21S11 10712 - - - - - - - -
D21S2055 2125 - - - - - - - -
D22S1045 10712 - - - - - - - -
D2S1338 10709 - - - - - - - -
D2S1360 2125 - - - - - - - -
D2S441 10713 - - - - - - - -
D3S1358 10711 - - - - - - - -
D3S1744 2125 - - - - - - - -
D4S2366 2125 - - - - - - - -
D5S2500 2125 - - - - - - - -
D5S818 6030 - - - - - - - -
D6S474 2125 - - - - - - - -
D7S1517 2125 - - - - - - - -
D7S820 6030 - - - - - - - -
D8S1132 2125 - - - - - - - -
D8S1179 10712 - - - - - - - -
FGA 10709 - - - - - - - -
Penta D 4064 - - - - - - - -
Penta E 4064 - - - - - - - -
SE33 8057 - - - - - - - -
TH01 10712 - - - - - - - -
TPOX 6030 - - - - - - - -
VWA 10706 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D10S2325 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D21S2055 D22S1045 D2S1338 D2S1360 D2S441 D3S1358 D3S1744 D4S2366 D5S2500 D5S818 D6S474 D7S1517 D7S820 D8S1132 D8S1179 FGA Penta D Penta E SE33 TH01 TPOX VWA
2.2 0.000369094
5 0.0000829187 0.000235294 0.000369094 0.0733268 0.00205377
6 0.000165837 0.00211765 0.0000829187 0.0000466766 0.0000829187 0.000492126 0.00135335 0.23329 0.000497512
6.2 0.0000466766
6.3 0.0000829187 0.000186174
7 0.000580431 0.0000466766 0.174824 0.00066335 0.0000466766 0.00116086 0.019403 0.00565945 0.162648 0.166402 0.00066335
7.3 0.0000620578 0.0000466766
8 0.00323383 0.0000933532 0.056 0.119735 0.0172704 0.0000933445 0.000886773 0.000235294 0.00364842 0.1699 0.0159167 0.0182087 0.011811 0.000124116 0.111417 0.543698
8.3 0.000466766
9 0.0271973 0.000186706 0.088 0.0790216 0.117905 0.00070028 0.0000933445 0.00140017 0.308235 0.00376471 0.0380597 0.159287 0.0129294 0.20657 0.0105807 0.000248231 0.166309 0.101493
9.1 0.0000829187
9.2 0.0000620578
9.3 0.308579
10 0.259204 0.000233383 0.141882 0.0626036 0.0573189 0.00863679 0.000606796 0.00214692 0.000560119 0.186362 0.000140043 0.000235294 0.152471 0.0978824 0.0620232 0.266335 0.0781367 0.104946 0.0887057 0.000124116 0.0113891 0.0616086 0.0000467028
10.1 0.000165837
10.2 0.000235294 0.0000466766 0.0000620578
10.3 0.0000829187 0.0000933445 0.0000829187 0.0000466766
11 0.309784 0.00275392 0.163294 0.313184 0.305032 0.0121382 0.00462099 0.0827033 0.135736 0.336834 0.00140043 0.0776471 0.271529 0.339386 0.000470588 0.204395 0.0784167 0.147146 0.110851 0.000620578 0.255224
11.2 0.000470588 0.000310289
11.3 0.0594138 0.0000829187
12 0.326534 0.0302931 0.166118 0.284826 0.296817 0.138796 0.0833178 0.128162 0.0127427 0.0000933794 0.0409783 0.000420129 0.000235294 0.184706 0.174824 0.3733 0.00211765 0.138474 0.14129 0.220349 0.200295 0.00440611 0.0358209 0.000373622
12.1 0.0000466766 0.000653473 0.000235294 0.0000466766 0.0000620578
12.2 0.000705882 0.0000466766 0.000980209 0.000705882 0.000310289
12.3 0.00158686
13 0.0610282 0.281693 0.116941 0.100083 0.177371 0.135808 0.23273 0.0663213 0.00490105 0.000186759 0.0289368 0.00317431 0.00305882 0.170588 0.0567059 0.170398 0.255529 0.0353234 0.324683 0.207923 0.101132 0.00887427 0.000829187 0.00214833
13.1 0.000470588
13.2 0.000235294 0.0158701 0.000235294 0.00198585
13.3 0.000140017 0.000373378 0.000186174
13.4 0.000615157
14 0.0106136 0.311706 0.0590588 0.000233361 0.0386401 0.0266057 0.168067 0.348628 0.0862037 0.0496639 0.000186759 0.294362 0.111007 0.105882 0.1 0.0548235 0.0107794 0.200941 0.000235294 0.00621891 0.000235294 0.212145 0.0706201 0.0537648 0.0291051 0.000165837 0.100644
14.1 0.0000466723 0.000235294 0.000470588 0.000492126
14.2 0.023525 0.00186174
14.3 0.00256697 0.0000466723 0.000186174
15 0.00140962 0.205471 0.0232941 0.0412116 0.000912106 0.0014003 0.142577 0.163835 0.136796 0.35773 0.000747035 0.0445253 0.254085 0.0644706 0.00517647 0.228235 0.00116086 0.128 0.000235294 0.000248756 0.000470588 0.106143 0.0000466897 0.0132874 0.0494587 0.0399652 0.10298
15.1 0.000235294
15.2 0.0000466853 0.0423357 0.00086881
15.3 0.0649678 0.0000466723 0.00086881
16 0.0000829187 0.133075 0.00541176 0.0297302 0.0000829187 0.0000933532 0.1338 0.0523245 0.121721 0.342186 0.0440751 0.00406049 0.248716 0.110588 0.0898824 0.0000829187 0.301647 0.00258824 0.0108235 0.0263723 0.000513587 0.00270669 0.046998 0.0479707 0.208294
16.1 0.000140017 0.0736471 0.000186174
16.2 0.0000466853 0.0207244 0.000558521
16.3 0.000140017 0.0518529 0.0016135
17 0.0316468 0.000941176 0.102726 0.10775 0.00410754 0.0498927 0.0870519 0.220702 0.0000466723 0.212352 0.307294 0.0188235 0.103765 0.00329412 0.113647 0.00350075 0.00116724 0.000123031 0.0436762 0.068636 0.2755
17.1 0.000326706 0.0214118 0.000046681 0.0000620578
17.2 0.00364078 0.000434405
17.3 0.0191356 0.133763 0.00111704
18 0.00252054 0.000470588 0.183562 0.0704015 0.00028006 0.00424718 0.007795 0.0832477 0.000705882 0.155448 0.190353 0.00305882 0.00705882 0.0310588 0.227294 0.00042009 0.0144738 0.000123031 0.0225148 0.0749659 0.208341
18.1 0.0157647 0.0000620578
18.2 0.0000466723 0.00158701 0.0000466897 0.000682636
18.3 0.0210959 0.0561001 0.00111704
19 0.00028006 0.11206 0.0420635 0.000233361 0.0014003 0.110655 0.00588235 0.0122304 0.156235 0.000235294 0.105176 0.154588 0.0690074 0.0114419 0.0695668 0.0864001
19.1 0.227059 0.0000933794 0.0000620578
19.2 0.0000933445 0.0000933707 0.00014003 0.000280138 0.00335112
19.3 0.0105946 0.0108746 0.000124116
20 0.000235294 0.118968 0.0204949 0.000233383 0.144598 0.0931765 0.000980301 0.0527059 0.112235 0.144706 0.136521 0.00775098 0.0485913 0.0140575
20.1 0.0000466853 0.036
20.2 0.0000933445 0.000466897 0.0103637
20.3 0.00154018 0.000653412 0.0000620578
21 0.117754 0.0106443 0.0306751 0.0701176 0.00776471 0.106353 0.114353 0.176814 0.00221457 0.0299739 0.00121427
21.1 0.00470588 0.000235294 0.000470588
21.2 0.002708 0.0158247
21.3 0.000280034 0.0000620578
22 0.106506 0.00569561 0.000705882 0.0284807 0.3 0.00117647 0.0924706 0.115294 0.180502 0.00123031 0.00906044
22.1 0.0000466853 0.000235294 0.0000466897
22.2 0.00910449 0.027926
22.3 0.000186689
23 0.0834967 0.00116713 0.00682353 0.103371 0.155294 0.104941 0.0814118 0.14824 0.000246063 0.0027926
23.2 0.000235294 0.00485573 0.0350627
24 0.0328106 0.000840336 0.0103529 0.10818 0.0821176 0.154353 0.0254118 0.13484 0.000620578
24.1 0.000235294 0.0000466897
24.2 0.000606796 0.000980484 0.0315874
25 0.013675 0.000140056 0.00028006 0.138118 0.102671 0.0927059 0.217176 0.00894118 0.082454 0.000372347
25.1 0.000235294
25.2 0.00042009 0.000186759 0.0369244
26 0.00308037 0.00214712 0.139529 0.0197497 0.0854118 0.0543529 0.000941176 0.0306751 0.000248231
26.2 0.0000933532 0.0000933794 0.0538662
27 0.000793429 0.0320668 0.0211765 0.00196097 0.0642353 0.0108235 0.00476235 0.000248231
27.1 0.0000620578
27.2 0.0748418
27.3 0.000235294 0.000186174
28 0.000140017 0.1573 0.00658824 0.000373518 0.0291765 0.00235294 0.000887104 0.000248231
28.1 0.0000466766 0.000235294
28.2 0.00014003 0.0781308
28.3 0.0000466766 0.000235294 0.0000620578
29 0.0000466723 0.212939 0.032 0.0000466897 0.012 0.00188235 0.000140069 0.000372347
29.2 0.000980209 0.066526
29.3 0.000233383 0.000124116
30 0.242858 0.0305882 0.00705882 0.000124116
30.1 0.000235294 0.0000620578
30.2 0.0406553 0.0533697
31 0.0743559 0.036 0.00117647 0.000310289
31.1 0.0000466766
31.2 0.0914395 0.0287328
31.3 0.0000466766
32 0.0132562 0.04 0.000470588 0.00105498
32.2 0.0940534 0.0124736
33 0.00158701 0.0522353 0.00589549
33.1 0.0000466766
33.2 0.0301998 0.0000466897 0.00477845
34 0.000233383 0.0588235 0.00310289
34.1 0.0000933532
34.2 0.00336072 0.00186174
35 0.000233383 0.0336471 0.00155145
35.2 0.000233383 0.000248231
36 0.0112941 0.000806752
36.2 0.0000620578
37 0.00188235 0.000310289
38 0.000470588 0.000124116

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