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African

Study statistics

Loci
22 Autosomal STRs
Allele type
Length-based alleles
Sample size
284
Location
Unknown

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Bibliographic information

Date published
Aug. 1, 2019
Title
Population Genetics Data for 22 Autosomal STR Loci in European, South Asian and African Populations Using SureID® 23comp Human DNA Identification Kit
Authors
Sasitaran Iyavoo, Olatunde Afolabi, Byron Boggi, Ausma Bernotaite, and Thomas Haizel
Journal
Forensic Science International
Abstract

Allele frequency data for 22 short tandem repeat loci; D18S1364, D1S1656, D13S325, D5S2800, D9S1122, D4S2366, D3S1744, D12S391, D11S2368, D21S2055, D20S482, D8S1132, D7S3048, D2S441, D19S253, D10S1248, D17S1301, D22-GATA198B05, D16S539, D6S474, D14S1434 and D15S659 from the SureID® 23comp Human DNA Identification Kit have been determined for unrelated individuals in European, South Asian and African populations. Deviations from Hardy–Weinberg equilibrium were observed in loci D1S1656 and D19S253 in European; D18S1364, D6S474 and D14S1434 in South Asian; and D9S1122 and D8S1132 in African populations (p-value $<$0.05). However, after Bonferroni correction no significant deviations were observed (p-value $<$0.002). The most discriminating loci were D1S1656 and D12S391 for European (PD=0.977), D21S2055 for South Asian (PD=0.980), and D21S2055 and D7S3048 for African (PD=0.972) populations. The match probabilities were 1 in 6.7×1025 for European, 1 in 1.4×1026 for South Asian and 1 in 1.6×1026 for African populations. These findings established the high discriminatory capacity and robustness of the tested STR loci for forensic identification and kinship testing.

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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 - 0.071 2.219 0.775 0.796 0.765 0.929 0.553 0.543
D11S2368 - 0.058 2.491 0.799 0.822 0.796 0.942 0.598 0.522
D12S391 - 0.033 3.021 0.835 0.868 0.853 0.967 0.665 0.225
D13S325 - 0.069 2.679 0.813 0.809 0.780 0.931 0.624 0.550
D14S1434 - 0.125 1.596 0.687 0.722 0.673 0.875 0.408 0.452
D15S659 - 0.044 2.254 0.778 0.837 0.817 0.956 0.559 0.221
D16S539 - 0.069 2.185 0.771 0.802 0.772 0.931 0.547 0.510
D17S1301 - 0.192 1.434 0.651 0.633 0.577 0.808 0.357 0.988
D18S1364 - 0.035 4.176 0.880 0.869 0.853 0.965 0.755 0.682
D19S253 - 0.054 3.302 0.849 0.834 0.812 0.946 0.692 0.747
D1S1656 - 0.043 4.057 0.877 0.850 0.833 0.957 0.748 0.452
D20S482 - 0.125 1.614 0.690 0.698 0.662 0.875 0.413 0.751
D21S2055 - 0.028 3.838 0.870 0.883 0.871 0.972 0.734 0.230
D22-GATA198B05 - 0.047 3.550 0.859 0.846 0.825 0.953 0.713 0.414
D2S441 - 0.092 2.219 0.775 0.769 0.734 0.908 0.553 0.461
D3S1744 - 0.080 1.844 0.729 0.773 0.745 0.920 0.474 0.399
D4S2366 - 0.111 2.152 0.768 0.749 0.708 0.889 0.540 0.430
D5S2800 - 0.080 2.119 0.764 0.785 0.750 0.920 0.534 0.752
D6S474 - 0.088 1.945 0.743 0.775 0.737 0.912 0.498 0.379
D7S3048 - 0.028 3.944 0.873 0.883 0.869 0.972 0.741 0.838
D8S1132 - 0.030 3.838 0.870 0.882 0.869 0.970 0.734 0.047
D9S1122 - 0.138 1.797 0.722 0.716 0.664 0.862 0.463 0.006

Allele frequencies

D10S1248 D11S2368 D12S391 D13S325 D14S1434 D15S659 D16S539 D17S1301 D18S1364 D19S253 D1S1656 D20S482 D21S2055 D22-GATA198B05 D2S441 D3S1744 D4S2366 D5S2800 D6S474 D7S3048 D8S1132 D9S1122
5 0.002
6 0.018
6.2 0.002
7 0.178
7.3 0.007
8 0.042 0.074
8.3 0.005
9 0.002 0.007 0.009 0.192 0.005 0.053 0.021 0.004 0.143 0.042
10 0.009 0.292 0.037 0.123 0.018 0.051 0.009 0.009 0.063 0.368 0.012
11 0.04 0.025 0.107 0.301 0.113 0.002 0.111 0.048 0.026 0.312 0.121 0.18
11.1 0.002
11.3 0.002 0.04
12 0.148 0.074 0.088 0.202 0.521 0.092 0.266 0.053 0.046 0.155 0.276 0.352
12.3 0.002
13 0.222 0.002 0.21 0.044 0.118 0.283 0.085 0.201 0.106 0.187 0.056 0.004 0.074 0.002 0.352
13.3 0.002 0.002
14 0.303 0.002 0.379 0.081 0.018 0.053 0.107 0.04 0.282 0.484 0.317 0.035 0.016 0.29 0.296 0.06
14.1 0.004
14.3 0.007 0.002
15 0.183 0.012 0.083 0.014 0.238 0.002 0.005 0.129 0.005 0.173 0.162 0.007 0.04 0.132 0.002 0.009 0.248 0.026 0.002
15.1 0.002 0.002
15.3 0.03
16 0.085 0.026 0.063 0.005 0.255 0.086 0.002 0.118 0.065 0.121 0.007 0.129 0.002 0.134 0.121
16.1 0.004 0.005
16.3 0.099
17 0.007 0.134 0.132 0.004 0.114 0.155 0.019 0.185 0.393 0.176 0.229 0.014 0.157
17.1 0.005
17.3 0.004 0.032
18 0.218 0.227 0.049 0.011 0.211 0.002 0.067 0.176 0.187 0.081 0.039 0.164
18.3 0.002 0.021
19 0.241 0.169 0.192 0.004 0.114 0.167 0.081 0.016 0.009 0.079 0.104
19.1 0.009 0.019
19.2 0.002
19.3 0.004 0.004
20 0.195 0.127 0.22 0.016 0.217 0.039 0.252 0.144 0.12
20.1 0.002 0.002
21 0.121 0.049 0.275 0.004 0.146 0.011 0.004 0.07 0.109
22 0.04 0.065 0.158 0.076 0.002 0.095 0.104
23 0.009 0.04 0.063 0.002 0.012 0.044 0.132 0.062
23.3 0.009
24 0.007 0.011 0.032 0.021 0.121 0.025
24.3 0.004
25 0.004 0.005 0.055 0.002 0.171 0.007
26 0.002 0.048 0.12
26.1 0.002
26.3 0.004
27 0.002 0.012
27.1 0.002
28 0.005 0.002
29 0.056
29.1 0.002
30 0.088
31 0.113
32 0.208
33 0.173
34 0.113
35 0.042
36 0.009
37 0.016
38 0.004
39 0.002

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