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European

Study statistics

Loci
22 Autosomal STRs
Allele type
Length-based alleles
Sample size
321
Location
Unknown

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Bibliographic information

Date published
Aug. 1, 2019
Title
Population Genetics Data for 22 Autosomal STR Loci in European, South Asian and African Populations Using SureID® 23comp Human DNA Identification Kit
Authors
Sasitaran Iyavoo, Olatunde Afolabi, Byron Boggi, Ausma Bernotaite, and Thomas Haizel
Journal
Forensic Science International
Abstract

Allele frequency data for 22 short tandem repeat loci; D18S1364, D1S1656, D13S325, D5S2800, D9S1122, D4S2366, D3S1744, D12S391, D11S2368, D21S2055, D20S482, D8S1132, D7S3048, D2S441, D19S253, D10S1248, D17S1301, D22-GATA198B05, D16S539, D6S474, D14S1434 and D15S659 from the SureID® 23comp Human DNA Identification Kit have been determined for unrelated individuals in European, South Asian and African populations. Deviations from Hardy–Weinberg equilibrium were observed in loci D1S1656 and D19S253 in European; D18S1364, D6S474 and D14S1434 in South Asian; and D9S1122 and D8S1132 in African populations (p-value $<$0.05). However, after Bonferroni correction no significant deviations were observed (p-value $<$0.002). The most discriminating loci were D1S1656 and D12S391 for European (PD=0.977), D21S2055 for South Asian (PD=0.980), and D21S2055 and D7S3048 for African (PD=0.972) populations. The match probabilities were 1 in 6.7×1025 for European, 1 in 1.4×1026 for South Asian and 1 in 1.6×1026 for African populations. These findings established the high discriminatory capacity and robustness of the tested STR loci for forensic identification and kinship testing.

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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 - 0.103 2.326 0.785 0.760 0.720 0.897 0.572 0.877
D11S2368 - 0.066 2.675 0.813 0.810 0.781 0.934 0.624 0.862
D12S391 - 0.023 4.115 0.879 0.896 0.885 0.977 0.752 0.431
D13S325 - 0.060 3.415 0.854 0.821 0.796 0.940 0.702 0.551
D14S1434 - 0.145 1.558 0.679 0.695 0.637 0.855 0.397 0.957
D15S659 - 0.047 2.767 0.819 0.840 0.818 0.953 0.635 0.543
D16S539 - 0.093 2.169 0.769 0.771 0.734 0.907 0.544 0.592
D17S1301 - 0.164 1.372 0.636 0.672 0.608 0.836 0.336 0.646
D18S1364 - 0.073 2.293 0.782 0.791 0.760 0.927 0.566 0.954
D19S253 - 0.081 1.726 0.710 0.773 0.740 0.919 0.444 0.015
D1S1656 - 0.023 4.338 0.885 0.900 0.889 0.977 0.764 0.026
D20S482 - 0.124 1.605 0.688 0.714 0.669 0.876 0.411 0.464
D21S2055 - 0.029 3.087 0.838 0.875 0.863 0.971 0.671 0.102
D22-GATA198B05 - 0.044 2.918 0.829 0.850 0.830 0.956 0.653 0.196
D2S441 - 0.102 2.229 0.776 0.751 0.713 0.898 0.555 0.753
D3S1744 - 0.055 2.918 0.829 0.820 0.797 0.945 0.653 0.999
D4S2366 - 0.073 2.229 0.776 0.791 0.763 0.927 0.555 0.739
D5S2800 - 0.119 1.726 0.710 0.729 0.680 0.881 0.444 0.695
D6S474 - 0.082 2.360 0.788 0.791 0.757 0.918 0.577 0.111
D7S3048 - 0.032 4.224 0.882 0.879 0.865 0.968 0.758 0.152
D8S1132 - 0.038 3.915 0.872 0.863 0.846 0.962 0.739 0.845
D9S1122 - 0.152 1.589 0.685 0.694 0.637 0.848 0.406 0.297

Allele frequencies

D10S1248 D11S2368 D12S391 D13S325 D14S1434 D15S659 D16S539 D17S1301 D18S1364 D19S253 D1S1656 D20S482 D21S2055 D22-GATA198B05 D2S441 D3S1744 D4S2366 D5S2800 D6S474 D7S3048 D8S1132 D9S1122
7 0.268 0.002
8 0.008 0.002 0.034 0.002 0.002
9 0.005 0.125 0.002 0.014 0.011 0.002 0.347 0.002
10 0.192 0.02 0.07 0.019 0.02 0.002 0.174 0.178 0.022
11 0.003 0.041 0.192 0.322 0.346 0.002 0.086 0.081 0.016 0.371 0.092 0.192
11.3 0.042
12 0.039 0.019 0.217 0.279 0.417 0.006 0.343 0.137 0.039 0.036 0.157 0.399
12.1 0.002
13 0.312 0.357 0.058 0.167 0.185 0.201 0.16 0.07 0.229 0.039 0.126 0.003 0.33
13.1 0.002
13.3 0.002
14 0.301 0.374 0.031 0.025 0.028 0.246 0.062 0.084 0.43 0.274 0.106 0.092 0.291 0.232 0.047
14.3 0.003 0.008
15 0.187 0.002 0.041 0.019 0.157 0.005 0.002 0.301 0.012 0.151 0.209 0.003 0.048 0.084 0.008 0.196 0.002 0.002 0.008
15.3 0.07
16 0.128 0.003 0.025 0.022 0.19 0.103 0.081 0.065 0.117 0.008 0.125 0.151 0.005 0.012 0.002
16.1 0.053
16.3 0.048
17 0.028 0.039 0.129 0.022 0.107 0.026 0.042 0.002 0.134 0.296 0.344 0.282 0.028 0.132
17.1 0.014
17.3 0.02 0.148
18 0.003 0.148 0.173 0.053 0.022 0.079 0.009 0.131 0.206 0.246 0.123 0.059 0.196
18.1 0.008
18.3 0.036 0.064
19 0.24 0.123 0.235 0.002 0.028 0.192 0.122 0.003 0.011 0.073 0.146
19.1 0.259
19.3 0.012 0.003
20 0.245 0.112 0.248 0.006 0.143 0.047 0.009 0.002 0.092 0.154
20.1 0.042
20.3 0.005
21 0.21 0.101 0.182 0.002 0.003 0.201 0.014 0.153 0.122
21.1 0.005
22 0.076 0.101 0.146 0.072 0.002 0.003 0.12 0.126
22.2 0.002
23 0.026 0.073 0.069 0.006 0.006 0.086 0.179 0.076
24 0.006 0.036 0.014 0.016 0.002 0.017 0.145 0.023
25 0.005 0.016 0.002 0.125 0.114 0.006
26 0.002 0.162 0.025
27 0.006 0.006
28 0.02
29 0.03
30 0.016
31 0.028
32 0.025
33 0.058
34 0.069
35 0.044
36 0.012
37 0.002

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