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South Asian

Study statistics

Loci
22 Autosomal STRs
Allele type
Length-based alleles
Sample size
315
Location
Unknown

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Bibliographic information

Date published
Aug. 1, 2019
Title
Population Genetics Data for 22 Autosomal STR Loci in European, South Asian and African Populations Using SureID® 23comp Human DNA Identification Kit
Authors
Sasitaran Iyavoo, Olatunde Afolabi, Byron Boggi, Ausma Bernotaite, and Thomas Haizel
Journal
Forensic Science International
Abstract

Allele frequency data for 22 short tandem repeat loci; D18S1364, D1S1656, D13S325, D5S2800, D9S1122, D4S2366, D3S1744, D12S391, D11S2368, D21S2055, D20S482, D8S1132, D7S3048, D2S441, D19S253, D10S1248, D17S1301, D22-GATA198B05, D16S539, D6S474, D14S1434 and D15S659 from the SureID® 23comp Human DNA Identification Kit have been determined for unrelated individuals in European, South Asian and African populations. Deviations from Hardy–Weinberg equilibrium were observed in loci D1S1656 and D19S253 in European; D18S1364, D6S474 and D14S1434 in South Asian; and D9S1122 and D8S1132 in African populations (p-value $<$0.05). However, after Bonferroni correction no significant deviations were observed (p-value $<$0.002). The most discriminating loci were D1S1656 and D12S391 for European (PD=0.977), D21S2055 for South Asian (PD=0.980), and D21S2055 and D7S3048 for African (PD=0.972) populations. The match probabilities were 1 in 6.7×1025 for European, 1 in 1.4×1026 for South Asian and 1 in 1.6×1026 for African populations. These findings established the high discriminatory capacity and robustness of the tested STR loci for forensic identification and kinship testing.

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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 - 0.084 2.283 0.781 0.783 0.748 0.916 0.564 0.106
D11S2368 - 0.065 2.813 0.822 0.816 0.789 0.935 0.641 0.149
D12S391 - 0.037 2.864 0.825 0.859 0.843 0.963 0.647 0.197
D13S325 - 0.064 2.461 0.797 0.812 0.784 0.936 0.593 0.467
D14S1434 - 0.125 1.712 0.708 0.728 0.682 0.875 0.441 0.043
D15S659 - 0.037 2.864 0.825 0.860 0.843 0.963 0.647 0.460
D16S539 - 0.074 2.218 0.775 0.794 0.764 0.926 0.553 0.285
D17S1301 - 0.193 1.346 0.629 0.629 0.576 0.807 0.327 0.065
D18S1364 - 0.057 2.045 0.756 0.821 0.796 0.943 0.519 0.012
D19S253 - 0.075 2.250 0.778 0.793 0.762 0.925 0.558 0.195
D1S1656 - 0.028 5.250 0.905 0.888 0.876 0.972 0.805 0.248
D20S482 - 0.145 1.559 0.679 0.684 0.638 0.855 0.397 0.684
D21S2055 - 0.020 3.663 0.863 0.901 0.891 0.980 0.722 0.589
D22-GATA198B05 - 0.045 2.972 0.832 0.844 0.824 0.955 0.659 0.480
D2S441 - 0.127 1.559 0.679 0.709 0.664 0.873 0.397 0.392
D3S1744 - 0.055 2.540 0.803 0.826 0.802 0.945 0.605 0.206
D4S2366 - 0.059 2.500 0.800 0.818 0.791 0.941 0.599 0.465
D5S2800 - 0.090 1.712 0.708 0.762 0.721 0.910 0.441 0.165
D6S474 - 0.085 1.770 0.717 0.776 0.740 0.915 0.456 0.017
D7S3048 - 0.029 4.038 0.876 0.879 0.866 0.971 0.747 0.681
D8S1132 - 0.040 2.500 0.800 0.853 0.834 0.960 0.599 0.133
D9S1122 - 0.144 1.641 0.695 0.703 0.646 0.856 0.421 0.940

Allele frequencies

D10S1248 D11S2368 D12S391 D13S325 D14S1434 D15S659 D16S539 D17S1301 D18S1364 D19S253 D1S1656 D20S482 D21S2055 D22-GATA198B05 D2S441 D3S1744 D4S2366 D5S2800 D6S474 D7S3048 D8S1132 D9S1122
6 0.002
7 0.005 0.248
8 0.005 0.057 0.035 0.032
9 0.014 0.152 0.005 0.008 0.006 0.003 0.284
10 0.133 0.052 0.119 0.013 0.03 0.014 0.005 0.273 0.163 0.025
10.1 0.002
11 0.016 0.092 0.2 0.325 0.216 0.124 0.152 0.008 0.433 0.002 0.16 0.249
11.3 0.049
12 0.017 0.052 0.144 0.216 0.535 0.017 0.308 0.084 0.044 0.06 0.003 0.156 0.378
12.1 0.005
12.3 0.006
13 0.167 0.356 0.073 0.119 0.194 0.263 0.176 0.119 0.224 0.011 0.129 0.002 0.005 0.302
13.1 0.003
14 0.306 0.002 0.343 0.032 0.011 0.035 0.165 0.06 0.086 0.478 0.154 0.084 0.098 0.279 0.254 0.037
14.1 0.002
14.3 0.002 0.003
15 0.241 0.006 0.017 0.179 0.003 0.235 0.01 0.184 0.186 0.008 0.011 0.071 0.01 0.003 0.321 0.006
15.3 0.024
16 0.186 0.016 0.016 0.008 0.003 0.17 0.11 0.141 0.051 0.132 0.002 0.14 0.01 0.133 0.003 0.005 0.003
16.1 0.146
16.3 0.021
17 0.062 0.049 0.137 0.005 0.002 0.097 0.048 0.06 0.229 0.271 0.262 0.173 0.044 0.076
17.1 0.013
17.3 0.003 0.043
18 0.005 0.121 0.238 0.056 0.002 0.024 0.113 0.016 0.002 0.078 0.192 0.292 0.1 0.044 0.216
18.1 0.025
18.3 0.016 0.013
19 0.216 0.165 0.237 0.005 0.038 0.002 0.124 0.173 0.01 0.011 0.094 0.197
19.1 0.11
19.3 0.003
20 0.243 0.103 0.251 0.01 0.156 0.057 0.044 0.159 0.154
20.1 0.011
21 0.233 0.097 0.203 0.002 0.19 0.005 0.137 0.125
21.1 0.006
22 0.086 0.114 0.148 0.073 0.002 0.098 0.097
23 0.029 0.071 0.065 0.002 0.01 0.002 0.067 0.184 0.086
24 0.005 0.025 0.019 0.014 0.002 0.03 0.113 0.03
24.3 0.002
25 0.006 0.005 0.175 0.09 0.003
26 0.002 0.002 0.14 0.03
26.3 0.002
27 0.017 0.003
28 0.017
29 0.027
30 0.025
31 0.04
32 0.052
33 0.048
34 0.076
35 0.044
36 0.005
37 0.006

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