👩‍🔬 leapdna

← Back to Explore

STRidER: Asia

Study statistics

Loci
40 Autosomal STRs
Allele type
Length-based alleles
Sample size
3000
Population
Unknown

Download

Bibliographic information

Date published
Nov. 7, 2024
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

leapdna checks

New! Learn more about automated checks

Normalized frequencies
🟢 Passed

This check verifies that allele frequencies for each locus add up to 1 within a specified tolerance.

Misspelled locus names
🟢 Passed

Looks for common misspellings such as changing thee number 0 for the letter O.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 4523 - - - - - - - -
D10S1248 4523 - - - - - - - -
D11S2368 500 - - - - - - - -
D12S391 4523 - - - - - - - -
D13S317 4523 - - - - - - - -
D13S325 500 - - - - - - - -
D14S1434 500 - - - - - - - -
D15S659 500 - - - - - - - -
D16S539 4523 - - - - - - - -
D17S1301 500 - - - - - - - -
D18S1364 500 - - - - - - - -
D18S51 4523 - - - - - - - -
D19S253 500 - - - - - - - -
D19S433 4523 - - - - - - - -
D1S1656 4523 - - - - - - - -
D20S482 500 - - - - - - - -
D21S11 4523 - - - - - - - -
D21S2055 500 - - - - - - - -
D22GATA198B05 500 - - - - - - - -
D22S1045 4523 - - - - - - - -
D2S1338 4523 - - - - - - - -
D2S441 4523 - - - - - - - -
D3S1358 4523 - - - - - - - -
D3S1744 500 - - - - - - - -
D4S2366 500 - - - - - - - -
D5S2800 500 - - - - - - - -
D5S818 4523 - - - - - - - -
D6S474 500 - - - - - - - -
D7S3048 500 - - - - - - - -
D7S820 4523 - - - - - - - -
D8S1132 500 - - - - - - - -
D8S1179 4523 - - - - - - - -
D9S1122 500 - - - - - - - -
FGA 4523 - - - - - - - -
Penta D 1000 - - - - - - - -
Penta E 1000 - - - - - - - -
SE33 3523 - - - - - - - -
TH01 4523 - - - - - - - -
TPOX 4523 - - - - - - - -
VWA 4523 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D11S2368 D12S391 D13S317 D13S325 D14S1434 D15S659 D16S539 D17S1301 D18S1364 D18S51 D19S253 D19S433 D1S1656 D20S482 D21S11 D21S2055 D22GATA198B05 D22S1045 D2S1338 D2S441 D3S1358 D3S1744 D4S2366 D5S2800 D5S818 D6S474 D7S3048 D7S820 D8S1132 D8S1179 D9S1122 FGA Penta D Penta E SE33 TH01 TPOX VWA
1 0.00055273 0.00276365 0.000110546 0.000331638
4 0.000110546
5 0.0005 0.049 0.000331638
5.2 0.0005
6 0.000442184 0.001 0.004 0.000110546 0.0005 0.13774 0.000331638
6.3 0.000709622
7 0.00608004 0.00265311 0.003 0.222 0.0274154 0.00751713 0.000110546 0.001 0.0365 0.006 0.288304 0.00055273
7.3 0.000709622 0.000110546
7.4 0.0005
8 0.00176874 0.292616 0.0118284 0.018 0.000221092 0.000221092 0.00254256 0.16604 0.0014371 0.076 0.002 0.0745081 0.574287
8.1 0.000110546 0.0005
8.4 0.0005
9 0.0268627 0.00221092 0.123369 0.001 0.006 0.185939 0.001 0.000221092 0.009 0.0071855 0.000994915 0.01 0.00254256 0.299 0.0591422 0.001 0.0749503 0.00176874 0.008 0.3175 0.012 0.000567698 0.365023 0.120606
9.1 0.00917533 0.00386911
9.2 0.000110546
9.3 0.000110546 0.0724077
10 0.216339 0.00055273 0.124364 0.29 0.037 0.120164 0.042 0.00165819 0.018 0.000331638 0.00364802 0.004 0.000442184 0.207937 0.107 0.218881 0.194451 0.135972 0.054 0.15 0.048 0.000141924 0.0593633 0.0436657 0.000110546
10.1 0.000884369 0.000442184
10.3 0.000110546
11 0.299138 0.00386911 0.227393 0.036 0.222 0.2935 0.292 0.001 0.00784877 0.147 0.00364802 0.0695335 0.007 0.17002 0.302786 0.000221092 0.172 0.282998 0.341809 0.123259 0.237 0.126 0.261 0.000425773 0.00187928 0.241875
11.1 0.000110546 0.000110546 0.00055273
11.2 0.00055273 0.001 0.003 0.000283849
11.3 0.141499 0.000110546
12 0.366239 0.046761 0.16405 0.018 0.163 0.258125 0.449 0.045 0.0683175 0.353 0.0600265 0.0475348 0.039 0.004 0.0028742 0.135198 0.00055273 0.001 0.243 0.241322 0.002 0.179306 0.126575 0.405 0.1415 0.1155 0.00312234 0.000331638 0.0175768 0.000110546
12.1 0.000110546 0.000110546
12.2 0.0071855 0.000567698
12.3 0.00265311 0.000110546
13 0.0727393 0.312072 0.0496352 0.261 0.059 0.112204 0.188 0.247 0.141941 0.16 0.238669 0.0993809 0.222 0.00630113 0.0151448 0.0043113 0.008 0.106 0.021 0.154986 0.345 0.0253151 0.171899 0.256 0.000221092 0.088 0.059 0.0058189 0.000773823 0.000994915
13.1 0.001
13.2 0.0368119 0.000283849
13.3 0.000110546 0.000331638 0.000141924
14 0.00972806 0.251603 0.001 0.000331638 0.0148132 0.384 0.037 0.0171346 0.023 0.142 0.176542 0.061 0.247181 0.102145 0.477 0.01 0.0397966 0.000773823 0.163608 0.0421181 0.117 0.066 0.238 0.0103913 0.244 0.00486403 0.165709 0.031 0.0425 0.0765 0.0107863 0.000221092 0.240217
14.1 0.000110546 0.000110546
14.2 0.0853416 0.000425773
14.3 0.000141924
15 0.000994915 0.244528 0.002 0.0122706 0.000663277 0.006 0.207 0.000994915 0.005 0.185 0.223745 0.007 0.0900951 0.263542 0.186 0.011 0.365244 0.000110546 0.0160292 0.286757 0.079 0.005 0.003 0.00221092 0.214 0.000221092 0.003 0.185165 0.007 0.0125 0.066 0.0139086 0.0447712
15.1 0.000110546
15.2 0.000331638 0.158855 0.000110546 0.000110546 0.000709622
15.3 0.00773823 0.000110546 0.000567698
16 0.106677 0.016 0.00541676 0.004 0.004 0.18 0.126 0.161839 0.001 0.0217776 0.2086 0.052 0.131 0.206942 0.0257572 0.00165819 0.343909 0.133 0.002 0.001 0.143 0.003 0.016 0.0728499 0.001 0.00254256 0.0035 0.065 0.0327846 0.152443
16.1 0.082 0.000141924
16.2 0.000663277 0.0347115 0.000110546 0.000283849
16.3 0.0145921 0.000141924
16.4 0.0005
17 0.0279682 0.048 0.0834623 0.012 0.061 0.043 0.0808092 0.00187928 0.0822463 0.003 0.188 0.187597 0.114857 0.241101 0.34 0.239 0.039 0.068 0.138 0.0128233 0.00121601 0.0565 0.0655691 0.24906
17.1 0.013
17.2 0.000221092 0.00497457 0.0005 0.000567698
17.3 0.000663277 0.0584789
17.4 0.002
18 0.00320584 0.143 0.185828 0.045 0.021 0.143 0.0456555 0.0127128 0.099 0.0191245 0.0845678 0.0725182 0.167 0.28 0.012 0.091 0.211 0.00210038 0.0164714 0.0005 0.0565 0.0739427 0.196109
18.1 0.013
18.2 0.000663277 0.000851547
18.3 0.000884369 0.0202299
18.4 0.0015
19 0.241 0.191687 0.167 0.003 0.062 0.0340482 0.00276365 0.244 0.00121601 0.199978 0.00784877 0.096 0.006 0.061 0.2 0.000110546 0.074287 0.0005 0.0405 0.0750781 0.0961751
19.1 0.108 0.000141924
19.2 0.000221092 0.000110546 0.00127732
19.3 0.000773823 0.00265311
20 0.266 0.168693 0.308 0.006 0.0222198 0.000221092 0.153 0.000110546 0.122927 0.000442184 0.045 0.025 0.075 0.124 0.0598054 0.0245 0.0591825 0.0187928
20.1 0.01 0.000141924
20.2 0.00132655 0.00482543
21 0.206 0.123701 0.231 0.0147026 0.11 0.0463188 0.012 0.106 0.105 0.135308 0.024 0.0354811 0.000884369
21.1 0.000709622
21.2 0.0133761 0.0242691
21.3 0.000110546
22 0.059 0.106124 0.141 0.011939 0.044 0.000110546 0.0449923 0.002 0.003 0.086 0.106 0.190471 0.0145 0.0110701 0.000331638
22.1 0.000141924
22.2 0.0120495 0.0227079
22.3 0.000221092
23 0.016 0.0717444 0.071 0.00342693 0.001 0.005 0.168693 0.165 0.186 0.069 0.167809 0.0105 0.00212887
23.2 0.00961751 0.0367584
24 0.002 0.0258678 0.017 0.00243201 0.026 0.132876 0.019 0.181 0.023 0.141941 0.003 0.000851547
24.2 0.0139288 0.0464093
24.3 0.000141924
25 0.0169136 0.001 0.000994915 0.000110546 0.131 0.0499668 0.098 0.004 0.0915322 0.0035 0.000425773
25.2 0.0071855 0.0475447
26 0.00420075 0.000221092 0.000442184 0.121 0.00674331 0.037 0.041897 0.001 0.000283849
26.1 0.000141924
26.2 0.00154765 0.0668464
26.3 0.002 0.000141924
27 0.00121601 0.00420075 0.014 0.00132655 0.006 0.0113862
27.2 0.000442184 0.0766392
27.3 0.001 0.000141924
28 0.062348 0.012 0.000110546 0.001 0.00320584 0.000567698
28.2 0.00121601 0.000110546 0.0826001
29 0.251824 0.056 0.000773823 0.000141924
29.2 0.000994915 0.0669884
29.3 0.000110546
30 0.243091 0.032 0.001 0.000110546 0.000425773
30.1 0.000110546
30.2 0.0334955 0.0530798
30.3 0.000994915
31 0.0692019 0.041 0.000283849
31.1 0.000442184
31.2 0.0821358 0.000110546 0.0330684
32 0.0255361 0.102 0.000141924
32.1 0.000110546 0.000110546
32.2 0.154875 0.0198694
32.3 0.000283849
33 0.00331638 0.124 0.000709622
33.1 0.000221092
33.2 0.0565996 0.0080897
34 0.000442184 0.07 0.000709622
34.2 0.00663277 0.00425773
35 0.00055273 0.034 0.000283849
35.1 0.000110546
35.2 0.00110546 0.000993471
36 0.000110546 0.008
36.2 0.000283849
37 0.000110546 0.002 0.000141924
99 0.000110546

Download CSV or select another format