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STRidER: Bosnia And Herzegowina

Study statistics

Loci
16 Autosomal STRs
Allele type
Unknown
Sample size
171
Population
Unknown
Location
Bosnia And Herzegowina
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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 171 - - - - - - - -
D12S391 171 - - - - - - - -
D16S539 171 - - - - - - - -
D18S51 171 - - - - - - - -
D19S433 171 - - - - - - - -
D1S1656 171 - - - - - - - -
D21S11 171 - - - - - - - -
D22S1045 171 - - - - - - - -
D2S1338 171 - - - - - - - -
D2S441 171 - - - - - - - -
D3S1358 171 - - - - - - - -
D8S1179 171 - - - - - - - -
FGA 171 - - - - - - - -
SE33 171 - - - - - - - -
TH01 171 - - - - - - - -
VWA 171 - - - - - - - -

Allele frequencies

D10S1248 D12S391 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D8S1179 FGA SE33 TH01 VWA
6 0.277778
7 0.131579
8 0.00292398 0.00584795 0.131579
8.3 0.00292398
9 0.0760234 0.00292398 0.00292398 0.00877193 0.19883
9.3 0.245614
10 0.0672515 0.00584795 0.210526 0.0584795 0.0116959
11 0.00292398 0.312865 0.00292398 0.00292398 0.119883 0.157895 0.277778 0.0321637
11.3 0.0672515
12 0.0555556 0.356725 0.102339 0.105263 0.160819 0.0146199 0.0438596 0.187135
12.3 0.00292398
13 0.233918 0.163743 0.128655 0.181287 0.0467836 0.0233918 0.00292398 0.342105 0.0116959
13.2 0.0204678
14 0.312865 0.00584795 0.0204678 0.163743 0.397661 0.0906433 0.0643275 0.315789 0.0935673 0.216374 0.0350877 0.111111
14.2 0.0555556
15 0.233918 0.0467836 0.166667 0.119883 0.154971 0.365497 0.0526316 0.266082 0.114035 0.0526316 0.125731
15.2 0.0350877
15.3 0.0584795
16 0.108187 0.0321637 0.154971 0.0497076 0.131579 0.295322 0.0321637 0.00292398 0.207602 0.0321637 0.0321637 0.204678
16.1 0.00292398
16.2 0.0292398
16.3 0.0175439 0.00292398
17 0.0497076 0.0964912 0.0935673 0.0497076 0.0877193 0.266082 0.204678 0.00292398 0.0789474 0.239766
17.2 0.00292398
17.3 0.0175439 0.125731
18 0.00292398 0.184211 0.0672515 0.0146199 0.0701754 0.21345 0.0730994 0.210526
18.2 0.00292398
18.3 0.0233918 0.0321637
19 0.119883 0.0643275 0.119883 0.0116959 0.0730994 0.0847953 0.0906433
19.2 0.00292398 0.00877193
19.3 0.0204678 0.0116959
20 0.116959 0.0233918 0.154971 0.119883 0.0438596 0.00584795
20.2 0.00877193
21 0.114035 0.0116959 0.0292398 0.207602 0.0263158
21.2 0.00292398 0.00584795
22 0.102339 0.00877193 0.0321637 0.248538 0.00292398
22.2 0.00877193 0.0233918
23 0.0818713 0.00292398 0.108187 0.140351
23.2 0.00877193 0.0204678
24 0.0263158 0.0701754 0.0906433
24.2 0.0263158
25 0.00584795 0.108187 0.0701754
25.2 0.0350877
26 0.00292398 0.00877193 0.0204678
26.2 0.0526316
27 0.00292398 0.0409357 0.00584795
27.2 0.0877193
28 0.166667
28.2 0.128655
29 0.204678
29.2 0.00292398 0.0497076
30 0.201754
30.2 0.0555556 0.0614035
31 0.0760234
31.2 0.114035 0.0233918
32 0.00584795
32.2 0.0818713 0.00584795
33 0.00292398 0.00292398
33.2 0.0438596 0.00584795
34 0.00292398
34.2 0.00292398
35 0.00292398
36 0.00877193

Locus histograms

D10S1248

D12S391

D16S539

D18S51

D19S433

D1S1656

D21S11

D22S1045

D2S1338

D2S441

D3S1358

D8S1179

FGA

SE33

TH01

VWA