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STRidER: Slovakia

Study statistics

Loci
16 Autosomal STRs
Allele type
Unknown
Sample size
247
Population
Unknown

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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 247 - - - - - - - -
D12S391 247 - - - - - - - -
D16S539 247 - - - - - - - -
D18S51 247 - - - - - - - -
D19S433 247 - - - - - - - -
D1S1656 247 - - - - - - - -
D21S11 247 - - - - - - - -
D22S1045 247 - - - - - - - -
D2S1338 247 - - - - - - - -
D2S441 247 - - - - - - - -
D3S1358 247 - - - - - - - -
D8S1179 246 - - - - - - - -
FGA 247 - - - - - - - -
SE33 245 - - - - - - - -
TH01 247 - - - - - - - -
VWA 247 - - - - - - - -

Allele frequencies

D10S1248 D12S391 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D8S1179 FGA SE33 TH01 VWA
6 0.230769
7 0.143725
8 0.00809717 0.0101626 0.123482
8.3 0.00202429
9 0.137652 0.0101626 0.200405
9.3 0.295547
10 0.0728745 0.00809717 0.00607287 0.180162 0.0447154 0.00404858
10.3 0.00202429
11 0.285425 0.0101215 0.0870445 0.204453 0.348178 0.0995935
11.3 0.0607287
12 0.0303644 0.287449 0.0991903 0.0910931 0.149798 0.0202429 0.0323887 0.144309 0.00204082
12.2 0.00404858
12.3 0.00404858
13 0.212551 0.180162 0.119433 0.293522 0.117409 0.00809717 0.0283401 0.341463 0.00612245 0.00202429
13.2 0.0222672 0.00204082
14 0.321862 0.0283401 0.161943 0.327935 0.0647773 0.0283401 0.301619 0.0890688 0.254065 0.0142857 0.119433
14.2 0.0121457
14.3 0.00202429
15 0.242915 0.0263158 0.131579 0.151822 0.121457 0.370445 0.0384615 0.265182 0.0752033 0.0489796 0.119433
15.2 0.0202429
15.3 0.0425101
16 0.119433 0.0161943 0.192308 0.0445344 0.121457 0.277328 0.034413 0.00404858 0.271255 0.0162602 0.00202429 0.0428571 0.192308
16.2 0.00202429 0.0202429 0.00204082
16.3 0.0364372
17 0.0647773 0.111336 0.117409 0.0607287 0.0769231 0.218623 0.194332 0.00406504 0.00202429 0.0795918 0.275304
17.2 0.00809717
17.3 0.0222672 0.123482
18 0.00809717 0.216599 0.0688259 0.00404858 0.0101215 0.0951417 0.168016 0.0222672 0.0693878 0.204453
18.2 0.00404858
18.3 0.0161943 0.0607287
19 0.11336 0.0445344 0.00404858 0.0991903 0.0121457 0.0931174 0.0938776 0.0769231
19.2 0.00408163
19.3 0.00404858 0.00202429
20 0.123482 0.0283401 0.11336 0.182186 0.0693878 0.0101215
20.2 0.00202429 0.00612245
21 0.107287 0.00809717 0.0242915 0.159919 0.022449
21.2 0.00202429 0.0142857
21.3 0.00202429
22 0.111336 0.00607287 0.0222672 0.165992 0.00612245
22.2 0.0182186 0.0204082
23 0.105263 0.121457 0.117409 0.00204082
23.2 0.00404858 0.0408163
24 0.0161943 0.00202429 0.107287 0.157895 0.00204082
24.2 0.00202429 0.0428571
25 0.00404858 0.139676 0.0546559
25.2 0.0285714
26 0.00202429 0.0222672 0.0161943
26.2 0.0571429
27 0.01417 0.00202429 0.00202429
27.2 0.0489796
28 0.137652 0.00204082
28.2 0.0857143
29 0.255061 0.00612245
29.2 0.00202429 0.0591837
29.3 0.00204082
30 0.192308
30.2 0.0708502 0.0510204
31 0.0607287
31.2 0.0789474 0.0326531
32 0.0161943
32.2 0.119433 0.0102041
33 0.00816327
33.2 0.0323887 0.00816327
34 0.00204082
34.2 0.0182186 0.00408163
35 0.00204082

Locus histograms

D10S1248

D12S391

D16S539

D18S51

D19S433

D1S1656

D21S11

D22S1045

D2S1338

D2S441

D3S1358

D8S1179

FGA

SE33

TH01

VWA