👩‍🔬 leapdna

← Back to Explore

Sweden

Study statistics

Loci
16 Autosomal STRs
Allele type
Length-based alleles
Sample size
425

Download

Bibliographic information

Date published
June 1, 2011
Title
Swedish Population Data and Concordance for the Kits PowerPlex® ESX 16 System, PowerPlex® ESI 16 System, AmpFlSTR® NGM™, AmpFlSTR® SGM Plus™ and Investigator ESSplex
Authors
Linda Albinsson, Lina Norén, Ronny Hedell, and Ricky Ansell
Journal
Forensic Science International: Genetics
Abstract

The European Standard Set of loci (ESS) has been extended with five additional short tandem repeat (STR) loci following the recommendations of the European Network of Forensic Science Institutes (ENFSI) and the European DNA Profiling Group (EDNAP) to increase the number of loci routinely used by the European forensic community. Subsequently, a new extended Swedish population database, based on 425 individuals, has been assembled using the new STR multiplex kits commercially available. Allele frequencies and statistical parameters of forensic interest for 15 autosomal STR loci (D3S1358, TH01, D21S11, D18S51, D10S1248, D1S1656, D2S1338, D16S539, D22S1045, vWA, D8S1179, FGA, D2S441, D12S391 and D19S433) were obtained from the analysis of the PowerPlex® ESX 16 System kit (Promega Corporation, USA). According to the data no evidence of deviations from Hardy–Weinberg equilibrium was found. The observed heterozygosity varies between 0.755 (TH01) and 0.892 (D1S1656). The power of discrimination was smallest for D22S1045 (0.869) and largest for D1S1656 (0.982) while the power of exclusion was smallest for TH01 (0.518) and largest for D1S1656 (0.778). A concordance study was performed on the five amplification systems: PowerPlex® ESX 16 System, PowerPlex® ESI 16 System (Promega Corporation, USA), AmpFlSTR® NGM™, AmpFlSTR® SGM Plus™ (Applied Biosystems, USA) and Investigator ESSplex (Qiagen, Germany) to reveal null alleles and other divergences between the kits. For the 425 DNA profiles included, AmpFlSTR® NGM™ revealed two null alleles, AmpFlSTR® SGM Plus™ revealed one, and Investigator ESSplex revealed a micro-variant, while the rest of the alleles showed full concordance between the kits tested.

leapdna checks

New! Learn more about automated checks

Normalized frequencies
🔴 Failed

This check verifies that allele frequencies for each locus add up to 1 within a specified tolerance.

Misspelled locus names
🟢 Passed

Looks for common misspellings such as changing thee number 0 for the letter O.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
D10S1248 - - - 0.795 0.756 - - - 0.793
D12S391 - - - 0.866 0.888 - - - 0.347
D16S539 - - - 0.757 0.763 - - - 0.946
D18S51 - - - 0.858 0.875 - - - 0.241
D19S443 - - - 0.816 0.775 - - - 0.292
D1S1656 - - - 0.892 0.906 - - - 0.457
D21S11 - - - 0.818 0.843 - - - 0.774
D22S1045 - - - 0.759 0.721 - - - 0.822
D2S1338 - - - 0.873 0.878 - - - 0.953
D2S441 - - - 0.776 0.746 - - - 0.337
D3S1358 - - - 0.816 0.787 - - - 0.204
D8S1179 - - - 0.792 0.784 - - - 0.497
FGA - - - 0.833 0.862 - - - 0.152
TH01 - - - 0.755 0.766 - - - 0.387
vWA - - - 0.802 0.805 - - - 0.972

Allele frequencies

D10S1248 D12S391 D16S539 D18S51 D19S443 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D8S1179 FGA TH01 vWA
5 0.001
6 0.195
7 0.191
8 0.009 0.004 0.011 0.092
9 0.12 0.008 0.157
9.3 0.357
10 0.041 0.011 0.007 0.188 0.088 0.007
11 0.007 0.3 0.004 0.002 0.077 0.134 0.375 0.006 0.083
11.3 0.051
12 0.027 0.316 0.138 0.072 0.132 0.012 0.038 0.131
12.2 0.001
12.3 0.001
13 0.301 0.176 0.121 0.2 0.052 0.005 0.028 0.004 0.358 0.001
13.2 0.024
14 0.31 0.035 0.199 0.374 0.08 0.047 0.27 0.106 0.226 0.094
14.2 0.019
14.3 0.001
15 0.206 0.052 0.002 0.138 0.188 0.103 0.354 0.041 0.274 0.07 0.09
15.2 0.032
15.3 0.081
16 0.12 0.019 0.117 0.058 0.104 0.356 0.031 0.005 0.241 0.022 0.21
16.2 0.022
16.3 0.059
17 0.027 0.11 0.106 0.005 0.048 0.085 0.198 0.229 0.002 0.001 0.265
17.1 0.001
17.2 0.002
17.3 0.025 0.147
18 0.001 0.189 0.072 0.001 0.009 0.007 0.099 0.131 0.026 0.242
18.3 0.008 0.085
19 0.11 0.047 0.112 0.009 0.053 0.079
19.3 0.002 0.013
20 0.114 0.022 0.156 0.001 0.175 0.017
21 0.117 0.015 0.021 0.18 0.002
22 0.117 0.006 0.037 0.17
22.2 0.015
23 0.087 0.002 0.093 0.132
23.2 0.004
24 0.038 0.001 0.113 0.142
24.2 0.001
25 0.008 0.001 0.113 0.074
25.2 0.001
26 0.004 0.001 0.022 0.025
27 0.001 0.034 0.005 0.004
28 0.186
28.1 0.001
29 0.184
29.2 0.001
29.3 0.002
30 0.257
30.2 0.051
31 0.081
31.2 0.073
32 0.011
32.2 0.081
33 0.001
33.2 0.031

Download CSV or select another format