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India

Study statistics

Loci
21 Autosomal STRs
Allele type
Unknown
Sample size
437
Population
Indian (Southeast Asian)
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Bibliographic information

Date published
Dec. 1, 2021
Title
Genetic Polymorphism of 21 STR Markers in the Representative Sample of Indian Population
Authors
Dinesh Chandra, Vikash Chandra Mishra, Archana Anthwal, Nikita Gupta, Amit Kr Bhardwaj, Anoushka Raina, Sneha Kumari, Nikki Dey, and Vimarsh Raina
Journal
Gene Reports
Abstract

The study of allele frequency and analysis of statistical parameters of 21 STR markers was done among 437 unrelated individuals representing different parts of India using the GlobalFiler™ Express PCR Amplification Kit (Thermo Fisher Scientific, USA). All the tested 21 STR loci were tested for Hardy- Weinberg equilibrium and all of them were fall under it. A total of 210 alleles and 975 genotypes were identified among the studied population after detailed statistical analysis. The identified allelic frequencies range from 0.001 to 0.408. Among all the tested STR loci, SE33 was found to have the most discriminating power and most polymorphic. The genetic relationship among the studied population and with the population of other countries was also performed to understand genetic differentiation among them. The obtained data set showed diverse polymorphism could be used in human identification and relationship establishment.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 437 - 0.124 0.716 0.724 0.654 0.876 0.449 0.999
D10S1248 437 - 0.086 0.741 0.775 0.726 0.914 0.519 0.298
D12S391 437 - 0.038 0.835 0.852 0.830 0.962 0.648 0.509
D13S317 437 - 0.063 0.805 0.808 0.772 0.937 0.571 0.806
D16S539 437 - 0.061 0.810 0.810 0.776 0.939 0.575 0.346
D18S51 437 - 0.036 0.835 0.856 0.835 0.964 0.655 0.643
D19S433 437 - 0.055 0.778 0.817 0.785 0.945 0.586 0.327
D1S1656 437 - 0.029 0.854 0.874 0.859 0.971 0.691 0.198
D21S11 437 - 0.037 0.874 0.858 0.838 0.963 0.659 0.962
D22S1045 437 - 0.107 0.755 0.744 0.683 0.893 0.476 0.999
D2S1338 437 - 0.028 0.890 0.876 0.861 0.972 0.695 0.853
D2S441 437 - 0.126 0.693 0.715 0.640 0.874 0.437 0.206
D3S1358 437 - 0.113 0.760 0.740 0.677 0.887 0.470 0.516
D5S818 437 - 0.123 0.780 0.724 0.654 0.877 0.448 0.639
D7S820 437 - 0.071 0.803 0.798 0.759 0.929 0.555 0.611
D8S1179 437 - 0.040 0.844 0.851 0.829 0.960 0.646 0.371
FGA 437 - 0.033 0.858 0.866 0.849 0.967 0.675 0.978
SE33 437 - 0.007 0.943 0.947 0.944 0.993 0.855 0.973
TH01 437 - 0.082 0.760 0.782 0.737 0.918 0.530 0.396
TPOX 437 - 0.132 0.666 0.714 0.638 0.868 0.435 0.461
vWA 437 - 0.065 0.789 0.807 0.771 0.935 0.569 0.795

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA SE33 TH01 TPOX vWA
6 0.001 0.27
7 0.003 0.014 0.002 0.029 0.001 0.146
8 0.006 0.197 0.08 0.001 0.035 0.001 0.213 0.013 0.125 0.362
9 0.017 0.089 0.168 0.003 0.002 0.003 0.001 0.002 0.032 0.065 0.008 0.283 0.149
9.3 0.168
10 0.211 0.001 0.074 0.098 0.007 0.002 0.009 0.002 0.303 0.105 0.205 0.156 0.008 0.103
11 0.302 0.009 0.249 0.303 0.023 0.005 0.199 0.294 0.408 0.001 0.359 0.278 0.09 0.001 0.349
11.3 0.046
12 0.363 0.024 0.265 0.181 0.073 0.066 0.12 0.001 0.074 0.331 0.176 0.103 0.01 0.034
12.2 0.007
13 0.09 0.129 0.079 0.141 0.132 0.295 0.113 0.002 0.018 0.001 0.159 0.031 0.18 0.018 0.003 0.003
13.2 0.017
14 0.007 0.265 0.031 0.027 0.254 0.248 0.096 0.082 0.135 0.039 0.01 0.002 0.208 0.027 0.132
14.2 0.071 0.001
14.3 0.002
15 0.001 0.297 0.005 0.001 0.001 0.169 0.126 0.149 0.35 0.011 0.317 0.152 0.019 0.077
15.2 0.065
15.3 0.024 0.008
16 0.215 0.021 0.136 0.057 0.143 0.185 0.011 0.001 0.301 0.084 0.039 0.225
16.2 0.025 0.001
16.3 0.031 0.007
17 0.053 0.134 0.071 0.009 0.062 0.073 0.062 0.24 0.017 0.074 0.269
17.2 0.002 0.003
18 0.006 0.253 0.047 0.007 0.16 0.097 0.002 0.007 0.116 0.203
18.2 0.002
18.3 0.009
19 0.17 0.035 0.001 0.177 0.003 0.061 0.087 0.077
19.3 0.003 0.006 0.002
20 0.116 0.023 0.106 0.122 0.06 0.013
20.2 0.002
21 0.104 0.015 0.038 0.138 0.035 0.002
21.1 0.003
21.2 0.007
22 0.088 0.006 0.085 0.152 0.01
22.2 0.015
23 0.063 0.003 0.159 0.164 0.001
23.2 0.04
24 0.027 0.001 0.101 0.178 0.001
24.2 0.038
25 0.013 0.001 0.085 0.104
25.2 0.039
26 0.003 0.001 0.013 0.055
26.2 0.001 0.04
27 0.014 0.002 0.014 0.002
27.2 0.043
28 0.154 0.001 0.003
28.2 0.055
29 0.174 0.001
29.2 0.006 0.05
30 0.179 0.001
30.2 0.033 0.049
31 0.057
31.2 0.133 0.026
32 0.006
32.2 0.171 0.026
33 0.001 0.002
33.2 0.065 0.008
34 0.002
34.2 0.006 0.005
35 0.001
35.2 0.001

Locus histograms

CSF1PO

D10S1248

D12S391

D13S317

D16S539

D18S51

D19S433

D1S1656

D21S11

D22S1045

D2S1338

D2S441

D3S1358

D5S818

D7S820

D8S1179

FGA

SE33

TH01

TPOX

vWA