­čĹęÔÇŹ­čöČ leapdna

ÔćÉ Back to Explore

Korean, South Korea

Study statistics

Loci
23 Autosomal STRs
Allele type
Length-based alleles
Sample size
452

Download

Bibliographic information

Date published
May 1, 2013
Title
Korean Population Genetic Data and Concordance for the PowerPlex® ESX 17, AmpFlSTR Identifiler®, and PowerPlex® 16 Systems
Authors
Seung Beom Hong, Soon Hee Kim, Ki Cheol Kim, Moon Hee Park, Jeung Yoon Lee, Joon Myong Song, Myun Soo Han, and Wook Kim
Journal
Forensic Science International: Genetics
Abstract

In case of paternity or maternity investigations with short tandem repeat (STR) analysis, deficient cases, missing person, or mutations are encountered and common STRs cannot provide sufficient forensic parameters. Thus, it is recommended that additional STRs are needed to complement conventional analysis for more reliable forensic information. We analyzed variation of 23 STRs contained in the new PowerPlex┬« ESX 17 kit (Promega) and two conventional kits of the AmpFlSTR Identifiler┬« (Applied Biosystems) and PowerPlex┬« 16 systems (Promega) in 452 randomly chosen individuals from Korea to provide an expanded and reliable Korean database. Allele frequencies and forensic parameters were used to evaluate suitability and robustness of the new kit for forensic genetic analysis as well as in concordance studies. The combined probability of match for the 16 loci in the PowerPlex┬« ESX 17 system was 2.76├Ś10Ôłĺ20. One genotyping discrepancy due to a null allele was observed at the D18S51 locus (the concordant rate=99.99%), showing a primer-binding site mutation in the sequence of the locus (G-to-A substitution at position 146 of Genbank accession number JX018211). Thus, the new kit is a valuable forensic tool and is suitable to extend the Korean population genetic data obtained with well-established polymerase chain reaction multiplex-kits of the AmpFlSTR Identifiler┬« and PowerPlex┬« 16 systems.

leapdna checks

New! Learn more about automated checks

Normalized frequencies
­ččó Passed

This check verifies that allele frequencies for each locus add up to 1 within a specified tolerance.

Misspelled locus names
­ččó Passed

Looks for common misspellings such as changing thee number 0 for the letter O.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO - - - 0.719 0.720 0.675 0.876 0.458 0.756
D10S1248 - - - 0.741 0.746 0.706 0.896 0.495 0.583
D12S391 - - - 0.852 0.830 0.808 0.946 0.698 0.140
D13S317 - - - 0.808 0.807 0.778 0.934 0.613 0.975
D16S539 - - - 0.772 0.783 0.747 0.916 0.548 0.151
D18S51 - - - 0.838 0.843 0.824 0.955 0.672 0.051
D19S433 - - - 0.790 0.790 0.760 0.927 0.580 0.875
D1S1656 - - - 0.847 0.842 0.824 0.957 0.690 0.675
D21S11 - - - 0.810 0.808 0.784 0.940 0.617 0.594
D22S1045 - - - 0.777 0.761 0.719 0.897 0.556 0.807
D2S1338 - - - 0.841 0.873 0.858 0.969 0.677 0.049
D2S441 - - - 0.754 0.769 0.735 0.914 0.517 0.229
D3S1358 - - - 0.701 0.713 0.663 0.869 0.430 0.882
D5S818 - - - 0.748 0.773 0.737 0.913 0.506 0.182
D7S820 - - - 0.785 0.780 0.746 0.916 0.572 0.810
D8S1179 - - - 0.823 0.845 0.825 0.955 0.642 0.241
FGA - - - 0.850 0.849 0.830 0.959 0.694 0.953
Penta D - - - 0.803 0.797 0.770 0.930 0.605 0.792
Penta E - - - 0.923 0.921 0.915 0.986 0.842 0.365
SE33 - - - 0.942 0.942 0.938 0.991 0.882 0.124
TH01 - - - 0.664 0.683 0.635 0.850 0.374 0.719
TPOX - - - 0.611 0.628 0.559 0.802 0.304 0.200
vWA - - - 0.825 0.796 0.764 0.923 0.647 0.325

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA Penta D Penta E SE33 TH01 TPOX vWA
5 0.0011 0.0907
6 0.0011 0.1626
7 0.0033 0.0066 0.0088 0.0033 0.2566 0.0011
8 0.0033 0.0022 0.2633 0.0011 0.0011 0.0111 0.1449 0.0011 0.0354 0.0033 0.0387 0.4889
9 0.0498 0.0011 0.1427 0.2732 0.0675 0.0597 0.0011 0.3374 0.0077 0.4701 0.1139
9.1 0.0354
9.3 0.0542
10 0.219 0.0011 0.1527 0.1261 0.0011 0.2257 0.1958 0.1737 0.135 0.1338 0.052 0.0177 0.0232
10.1 0.0033
11 0.2301 0.0033 0.229 0.2555 0.0022 0.0033 0.0498 0.1615 0.3551 0.3263 0.3241 0.0697 0.1527 0.1051 0.3462
11.3 0.0221
12 0.4148 0.0907 0.1637 0.2279 0.0509 0.0288 0.0321 0.0066 0.2035 0.0066 0.2467 0.2445 0.125 0.1781 0.1095 0.0243
12.2 0.0033
13 0.0708 0.3684 0.0365 0.0996 0.2069 0.2887 0.1162 0.0022 0.0553 0.0011 0.1327 0.0398 0.2146 0.1217 0.0465 0.0022
13.2 0.0299
14 0.01 0.2644 0.0022 0.0077 0.0155 0.2334 0.2998 0.0774 0.0055 0.0929 0.0454 0.0133 0.0044 0.1969 0.0299 0.052 0.0055 0.2013
14.2 0.1018 0.0011
15 0.0022 0.1903 0.0166 0.0011 0.1914 0.0608 0.2577 0.2865 0.0066 0.3905 0.1604 0.0066 0.1206 0.01 0.0254
15.2 0.1471
16 0.0653 0.0022 0.115 0.0077 0.2345 0.2699 0.0055 0.3197 0.0808 0.0841 0.0332 0.1903
16.2 0.0243
16.3 0.0133
17 0.0111 0.0863 0.0542 0.0896 0.2412 0.0885 0.1637 0.0144 0.0011 0.0708 0.0608 0.292
17.2 0.0033
17.3 0.0619
18 0.0022 0.2467 0.0332 0.0144 0.0199 0.1316 0.0675 0.0011 0.0243 0.0863 0.0664 0.1869
18.2 0.0011 0.0011
18.3 0.0442
19 0.2445 0.0553 0.0066 0.1737 0.0044 0.0597 0.0531 0.0907 0.0852
19.2 0.0011
19.3 0.0044
20 0.1571 0.0188 0.0011 0.1195 0.0011 0.0575 0.0487 0.0796 0.0177
20.2 0.0011 0.0044
20.3 0.0022 0.0022
21 0.1095 0.0188 0.0265 0.0929 0.0321 0.0498 0.0011
21.2 0.0055 0.01
22 0.0675 0.0111 0.0376 0.1969 0.0166 0.031
22.2 0.0055 0.0277
23 0.031 0.0022 0.1659 0.2378 0.0122 0.0088
23.2 0.0033 0.0465
24 0.0177 0.0022 0.1482 0.1737 0.0088 0.0011
24.2 0.0022 0.0454
25 0.0111 0.0033 0.0808 0.0996
25.2 0.0033 0.0597
26 0.0033 0.0011 0.0177 0.0243
26.2 0.0752
27 0.0022 0.0044 0.0022 0.0088 0.0011
27.2 0.0642
28 0.052 0.0011 0.0022
28.2 0.0022 0.083
29 0.2301 0.0011
29.2 0.0022 0.0642
30 0.3208 0.0011
30.1 0.0011
30.2 0.0055 0.0376
30.3 0.0044
31 0.0985
31.2 0.0531 0.021
31.3 0.0011
32 0.0321
32.1 0.0011
32.2 0.135 0.0088
33 0.0033
33.2 0.0442 0.0077
34 0.0044
34.2 0.0055

Download CSV or select another format