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STRidER: Thailand

Study statistics

Loci
21 Autosomal STRs
Allele type
Unknown
Sample size
3000
Population
Unknown

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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 3000 - - - - - - - -
D10S1248 3000 - - - - - - - -
D12S391 3000 - - - - - - - -
D13S317 3000 - - - - - - - -
D16S539 3000 - - - - - - - -
D18S51 3000 - - - - - - - -
D19S433 3000 - - - - - - - -
D1S1656 3000 - - - - - - - -
D21S11 3000 - - - - - - - -
D22S1045 3000 - - - - - - - -
D2S1338 3000 - - - - - - - -
D2S441 3000 - - - - - - - -
D3S1358 3000 - - - - - - - -
D5S818 3000 - - - - - - - -
D7S820 3000 - - - - - - - -
D8S1179 3000 - - - - - - - -
FGA 3000 - - - - - - - -
SE33 3000 - - - - - - - -
TH01 3000 - - - - - - - -
TPOX 3000 - - - - - - - -
VWA 3000 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA SE33 TH01 TPOX VWA
1 0.000833333 0.00416667 0.000166667 0.0005
5 0.000333333
6 0.000666667 0.000166667 0.106 0.000166667
7 0.00566667 0.0035 0.0275 0.0065 0.296 0.0005
8 0.00166667 0.319333 0.011 0.000333333 0.00133333 0.1665 0.001 0.0728333 0.58
9 0.0261667 0.000166667 0.1325 0.188 0.000166667 0.0055 0.00116667 0.00133333 0.0525 0.0718333 0.001 0.382333 0.120167
9.1 0.00966667 0.00233333
9.3 0.000166667 0.076
10 0.2015 0.000333333 0.132667 0.121833 0.00166667 0.000333333 0.00383333 0.000166667 0.213833 0.229333 0.176833 0.146167 0.064 0.0346667
10.1 0.001 0.000333333
10.3 0.000166667
11 0.306167 0.00383333 0.226667 0.283667 0.00583333 0.00216667 0.0711667 0.182667 0.289167 0.288667 0.366333 0.116333 0.000333333 0.00216667 0.246167
11.1 0.000166667 0.000333333
11.2 0.000333333
11.3 0.163667 0.000166667
12 0.372833 0.0431667 0.137833 0.267 0.059 0.0581667 0.034 0.00183333 0.132667 0.000666667 0.229 0.177 0.116333 0.00266667 0.000333333 0.0173333
12.1 0.000166667
12.2 0.00766667 0.000666667
12.3 0.003 0.000166667
13 0.0756667 0.333833 0.036 0.111333 0.130833 0.248833 0.103833 0.00766667 0.018 0.00466667 0.157667 0.025 0.172 0.00416667 0.000666667 0.001
13.2 0.0341667 0.000166667
13.3 0.000166667
14 0.00966667 0.228833 0.000166667 0.01 0.0165 0.178 0.249667 0.105 0.0398333 0.000333333 0.151 0.04 0.011 0.00583333 0.1665 0.00366667 0.000333333 0.255333
14.1 0.000166667
14.2 0.09 0.0005
14.3 0.000166667
15 0.000666667 0.247167 0.00983333 0.000833333 0.000666667 0.246833 0.0846667 0.275333 0.361167 0.000166667 0.0148333 0.293167 0.003 0.000333333 0.188833 0.0111667 0.0326667
15.2 0.165833 0.000833333
15.3 0.0045 0.000166667 0.000666667
16 0.111667 0.00483333 0.169 0.0171667 0.208333 0.187167 0.017 0.00116667 0.342167 0.0765 0.00333333 0.0283333 0.1335
16.1 0.000166667
16.2 0.0296667 0.000333333
16.3 0.00866667 0.000166667
17 0.0276667 0.0851667 0.08 0.00133333 0.0855 0.1965 0.1005 0.238 0.0131667 0.00133333 0.064 0.250667
17.2 0.00383333 0.000666667
17.3 0.000666667 0.0561667
18 0.0025 0.191167 0.042 0.0135 0.0221667 0.0833333 0.072 0.00183333 0.0171667 0.0681667 0.2005
18.2 0.0005 0.001
18.3 0.000333333 0.0201667
19 0.1975 0.0321667 0.00216667 0.000666667 0.209667 0.009 0.07 0.077 0.1045
19.1 0.000166667
19.2 0.000333333 0.000166667 0.0015
19.3 0.000166667 0.00233333
20 0.175167 0.022 0.000166667 0.1095 0.000333333 0.0605 0.0618333 0.0205
20.1 0.000166667
20.2 0.00183333 0.0045
21 0.1275 0.0135 0.0445 0.132167 0.0385 0.000833333
21.1 0.000833333
21.2 0.016 0.0153333
21.3 0.000166667
22 0.1035 0.012 0.0515 0.201667 0.0126667 0.0005
22.1 0.000166667
22.2 0.0143333 0.0235
23 0.063 0.0035 0.185167 0.170833 0.0025
23.2 0.0106667 0.0396667
24 0.0226667 0.002 0.139833 0.129 0.000833333
24.2 0.0161667 0.0496667
24.3 0.000166667
25 0.0131667 0.001 0.000166667 0.0503333 0.0883333 0.0005
25.2 0.00733333 0.0511667
26 0.00383333 0.000333333 0.000166667 0.00683333 0.0421667 0.000333333
26.1 0.000166667
26.2 0.0015 0.0698333
26.3 0.000166667
27 0.001 0.00333333 0.00116667 0.00983333
27.2 0.0005 0.0813333
27.3 0.000166667
28 0.052 0.000166667 0.00283333 0.000666667
28.2 0.000833333 0.000166667 0.0896667
29 0.244 0.000666667 0.000166667
29.2 0.000833333 0.0723333
29.3 0.000166667
30 0.247167 0.0005
30.1 0.000166667
30.2 0.0421667 0.0548333
30.3 0.001
31 0.0715 0.000166667
31.1 0.000666667
31.2 0.0773333 0.0303333
32 0.0281667 0.000166667
32.1 0.000166667
32.2 0.161667 0.0166667
32.3 0.000333333
33 0.00333333
33.1 0.000333333
33.2 0.0566667 0.00833333
34 0.000166667
34.2 0.00733333 0.00416667
35.1 0.000166667
35.2 0.00133333 0.001
36.2 0.000166667
99 0.000166667

Locus histograms

CSF1PO

D10S1248

D12S391

D13S317

D16S539

D18S51

D19S433

D1S1656

D21S11

D22S1045

D2S1338

D2S441

D3S1358

D5S818

D7S820

D8S1179

FGA

SE33

TH01

TPOX

VWA