India
Study statistics
- Loci
- 21 Autosomal STRs
- Allele type
- Length-based alleles
- Sample size
- 437
- Population
-
Indian (Southeast Asian)
More studies with this population - Location
-
India
More studies with this location
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Bibliographic information
- Date published
- Dec. 1, 2021
- Title
- Genetic Polymorphism of 21 STR Markers in the Representative Sample of Indian Population
- Authors
- Dinesh Chandra, Vikash Chandra Mishra, Archana Anthwal, Nikita Gupta, Amit Kr Bhardwaj, Anoushka Raina, Sneha Kumari, Nikki Dey, and Vimarsh Raina
- Journal
- Gene Reports
- Abstract
-
The study of allele frequency and analysis of statistical parameters of 21 STR markers was done among 437 unrelated individuals representing different parts of India using the GlobalFiler™ Express PCR Amplification Kit (Thermo Fisher Scientific, USA). All the tested 21 STR loci were tested for Hardy- Weinberg equilibrium and all of them were fall under it. A total of 210 alleles and 975 genotypes were identified among the studied population after detailed statistical analysis. The identified allelic frequencies range from 0.001 to 0.408. Among all the tested STR loci, SE33 was found to have the most discriminating power and most polymorphic. The genetic relationship among the studied population and with the population of other countries was also performed to understand genetic differentiation among them. The obtained data set showed diverse polymorphism could be used in human identification and relationship establishment.
leapdna checks
- Normalized frequencies
-
🔴 Failed
This check verifies that allele frequencies for each locus add up to 1 within a specified tolerance.
Ran with tolerance = 0.001. Max. deviation from 1: -0.0060 at SE33.
- Misspelled locus names
-
🟢 Passed
Looks for common misspellings such as changing thee number 0 for the letter O.
Forensic parameters
Locus | # | MP | PI | Hobs | Hexp | PIC | PD | PE | HWE |
---|---|---|---|---|---|---|---|---|---|
CSF1PO | 437 | - | 0.124 | 0.716 | 0.724 | 0.654 | 0.876 | 0.449 | 0.999 |
D10S1248 total frequency: 0.999 | 437 | - | 0.086 | 0.741 | 0.775 | 0.726 | 0.914 | 0.519 | 0.298 |
D12S391 | 437 | - | 0.038 | 0.835 | 0.852 | 0.830 | 0.962 | 0.648 | 0.509 |
D13S317 total frequency: 0.999 | 437 | - | 0.063 | 0.805 | 0.808 | 0.772 | 0.937 | 0.571 | 0.806 |
D16S539 total frequency: 0.999 | 437 | - | 0.061 | 0.810 | 0.810 | 0.776 | 0.939 | 0.575 | 0.346 |
D18S51 total frequency: 0.999 | 437 | - | 0.036 | 0.835 | 0.856 | 0.835 | 0.964 | 0.655 | 0.643 |
D19S433 total frequency: 0.998 | 437 | - | 0.055 | 0.778 | 0.817 | 0.785 | 0.945 | 0.586 | 0.327 |
D1S1656 total frequency: 0.999 | 437 | - | 0.029 | 0.854 | 0.874 | 0.859 | 0.971 | 0.691 | 0.198 |
D21S11 | 437 | - | 0.037 | 0.874 | 0.858 | 0.838 | 0.963 | 0.659 | 0.962 |
D22S1045 total frequency: 0.998 | 437 | - | 0.107 | 0.755 | 0.744 | 0.683 | 0.893 | 0.476 | 0.999 |
D2S1338 | 437 | - | 0.028 | 0.890 | 0.876 | 0.861 | 0.972 | 0.695 | 0.853 |
D2S441 total frequency: 0.998 | 437 | - | 0.126 | 0.693 | 0.715 | 0.640 | 0.874 | 0.437 | 0.206 |
D3S1358 total frequency: 0.999 | 437 | - | 0.113 | 0.760 | 0.740 | 0.677 | 0.887 | 0.470 | 0.516 |
D5S818 total frequency: 0.999 | 437 | - | 0.123 | 0.780 | 0.724 | 0.654 | 0.877 | 0.448 | 0.639 |
D7S820 | 437 | - | 0.071 | 0.803 | 0.798 | 0.759 | 0.929 | 0.555 | 0.611 |
D8S1179 | 437 | - | 0.040 | 0.844 | 0.851 | 0.829 | 0.960 | 0.646 | 0.371 |
FGA total frequency: 0.999 | 437 | - | 0.033 | 0.858 | 0.866 | 0.849 | 0.967 | 0.675 | 0.978 |
SE33 total frequency: 0.994 | 437 | - | 0.007 | 0.943 | 0.947 | 0.944 | 0.993 | 0.855 | 0.973 |
TH01 | 437 | - | 0.082 | 0.760 | 0.782 | 0.737 | 0.918 | 0.530 | 0.396 |
TPOX | 437 | - | 0.132 | 0.666 | 0.714 | 0.638 | 0.868 | 0.435 | 0.461 |
vWA total frequency: 1.001 | 437 | - | 0.065 | 0.789 | 0.807 | 0.771 | 0.935 | 0.569 | 0.795 |
Allele frequencies
CSF1PO | D10S1248 | D12S391 | D13S317 | D16S539 | D18S51 | D19S433 | D1S1656 | D21S11 | D22S1045 | D2S1338 | D2S441 | D3S1358 | D5S818 | D7S820 | D8S1179 | FGA | SE33 | TH01 | TPOX | vWA | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6 | 0.001 | 0.27 | |||||||||||||||||||
7 | 0.003 | 0.014 | 0.002 | 0.029 | 0.001 | 0.146 | |||||||||||||||
8 | 0.006 | 0.197 | 0.08 | 0.001 | 0.035 | 0.001 | 0.213 | 0.013 | 0.125 | 0.362 | |||||||||||
9 | 0.017 | 0.089 | 0.168 | 0.003 | 0.002 | 0.003 | 0.001 | 0.002 | 0.032 | 0.065 | 0.008 | 0.283 | 0.149 | ||||||||
9.3 | 0.168 | ||||||||||||||||||||
10 | 0.211 | 0.001 | 0.074 | 0.098 | 0.007 | 0.002 | 0.009 | 0.002 | 0.303 | 0.105 | 0.205 | 0.156 | 0.008 | 0.103 | |||||||
11 | 0.302 | 0.009 | 0.249 | 0.303 | 0.023 | 0.005 | 0.199 | 0.294 | 0.408 | 0.001 | 0.359 | 0.278 | 0.09 | 0.001 | 0.349 | ||||||
11.3 | 0.046 | ||||||||||||||||||||
12 | 0.363 | 0.024 | 0.265 | 0.181 | 0.073 | 0.066 | 0.12 | 0.001 | 0.074 | 0.331 | 0.176 | 0.103 | 0.01 | 0.034 | |||||||
12.2 | 0.007 | ||||||||||||||||||||
13 | 0.09 | 0.129 | 0.079 | 0.141 | 0.132 | 0.295 | 0.113 | 0.002 | 0.018 | 0.001 | 0.159 | 0.031 | 0.18 | 0.018 | 0.003 | 0.003 | |||||
13.2 | 0.017 | ||||||||||||||||||||
14 | 0.007 | 0.265 | 0.031 | 0.027 | 0.254 | 0.248 | 0.096 | 0.082 | 0.135 | 0.039 | 0.01 | 0.002 | 0.208 | 0.027 | 0.132 | ||||||
14.2 | 0.071 | 0.001 | |||||||||||||||||||
14.3 | 0.002 | ||||||||||||||||||||
15 | 0.001 | 0.297 | 0.005 | 0.001 | 0.001 | 0.169 | 0.126 | 0.149 | 0.35 | 0.011 | 0.317 | 0.152 | 0.019 | 0.077 | |||||||
15.2 | 0.065 | ||||||||||||||||||||
15.3 | 0.024 | 0.008 | |||||||||||||||||||
16 | 0.215 | 0.021 | 0.136 | 0.057 | 0.143 | 0.185 | 0.011 | 0.001 | 0.301 | 0.084 | 0.039 | 0.225 | |||||||||
16.2 | 0.025 | 0.001 | |||||||||||||||||||
16.3 | 0.031 | 0.007 | |||||||||||||||||||
17 | 0.053 | 0.134 | 0.071 | 0.009 | 0.062 | 0.073 | 0.062 | 0.24 | 0.017 | 0.074 | 0.269 | ||||||||||
17.2 | 0.002 | 0.003 | |||||||||||||||||||
18 | 0.006 | 0.253 | 0.047 | 0.007 | 0.16 | 0.097 | 0.002 | 0.007 | 0.116 | 0.203 | |||||||||||
18.2 | 0.002 | ||||||||||||||||||||
18.3 | 0.009 | ||||||||||||||||||||
19 | 0.17 | 0.035 | 0.001 | 0.177 | 0.003 | 0.061 | 0.087 | 0.077 | |||||||||||||
19.3 | 0.003 | 0.006 | 0.002 | ||||||||||||||||||
20 | 0.116 | 0.023 | 0.106 | 0.122 | 0.06 | 0.013 | |||||||||||||||
20.2 | 0.002 | ||||||||||||||||||||
21 | 0.104 | 0.015 | 0.038 | 0.138 | 0.035 | 0.002 | |||||||||||||||
21.1 | 0.003 | ||||||||||||||||||||
21.2 | 0.007 | ||||||||||||||||||||
22 | 0.088 | 0.006 | 0.085 | 0.152 | 0.01 | ||||||||||||||||
22.2 | 0.015 | ||||||||||||||||||||
23 | 0.063 | 0.003 | 0.159 | 0.164 | 0.001 | ||||||||||||||||
23.2 | 0.04 | ||||||||||||||||||||
24 | 0.027 | 0.001 | 0.101 | 0.178 | 0.001 | ||||||||||||||||
24.2 | 0.038 | ||||||||||||||||||||
25 | 0.013 | 0.001 | 0.085 | 0.104 | |||||||||||||||||
25.2 | 0.039 | ||||||||||||||||||||
26 | 0.003 | 0.001 | 0.013 | 0.055 | |||||||||||||||||
26.2 | 0.001 | 0.04 | |||||||||||||||||||
27 | 0.014 | 0.002 | 0.014 | 0.002 | |||||||||||||||||
27.2 | 0.043 | ||||||||||||||||||||
28 | 0.154 | 0.001 | 0.003 | ||||||||||||||||||
28.2 | 0.055 | ||||||||||||||||||||
29 | 0.174 | 0.001 | |||||||||||||||||||
29.2 | 0.006 | 0.05 | |||||||||||||||||||
30 | 0.179 | 0.001 | |||||||||||||||||||
30.2 | 0.033 | 0.049 | |||||||||||||||||||
31 | 0.057 | ||||||||||||||||||||
31.2 | 0.133 | 0.026 | |||||||||||||||||||
32 | 0.006 | ||||||||||||||||||||
32.2 | 0.171 | 0.026 | |||||||||||||||||||
33 | 0.001 | 0.002 | |||||||||||||||||||
33.2 | 0.065 | 0.008 | |||||||||||||||||||
34 | 0.002 | ||||||||||||||||||||
34.2 | 0.006 | 0.005 | |||||||||||||||||||
35 | 0.001 | ||||||||||||||||||||
35.2 | 0.001 |