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Rajasthan, India

Study statistics

Loci
22 Autosomal STRs
Allele type
Length-based alleles
Sample size
595
Population
Unknown
Location
Rajasthan, India
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Bibliographic information

Date published
June 1, 2021
Title
Genomic Diversity at 22 STR Loci (Extended CODIS STR) in the Population of Rajasthan, India
Authors
Anand Kumar, Rajesh Kumar, R. K. Kumawat, Pankaj Shrivastava, and Gyaneshwer Chaubey
Journal
Gene Reports
Abstract

This study presents genetic diversity at 22 autosomal STR loci (extended CODIS STR) in the population of Rajasthan. It provides an allelic database of this population for the purpose of forensic inference. 595 unrelated healthy individuals residing in the state were randomly selected from the routine casework of the laboratory. Compliance of ethical standards was ensured during the collection of blood samples. The allele 15 of locus D22S1045 was found to be the most frequent allele among all the studied genetic markers. The matching probability was found to be 1.80 × 10−26 at all the studied markers. The loci Penta E and TPOX were found to be highest and least forensic importance respectively, among all the studied loci. The heterozygosity ranged from 0.711 for locus TPOX to 0.926 for the locus Penta E. The discrimination and exclusion power were found as 1 and 0.999999998292 respectively at all the studied loci. Overall, the highest polymorphism was observed 0.907 for locus Penta E among the studied markers in the population of Rajasthan. In population differentiation test, the population of Rajasthan showed a greater genetic affinity with north-western and central Indian populations than southern and eastern Indian, as well as East Asian populations.

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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO - 0.124 1.730 0.711 0.724 0.678 0.876 0.445 0.741
D10S1248 - 0.091 2.306 0.783 0.773 0.737 0.909 0.568 0.057
D12S391 - 0.033 3.269 0.847 0.865 0.851 0.967 0.689 0.726
D13S317 - 0.071 2.220 0.775 0.798 0.769 0.929 0.553 0.240
D16S539 - 0.067 2.656 0.812 0.801 0.775 0.933 0.621 0.735
D18S51 - 0.041 3.500 0.857 0.848 0.832 0.959 0.709 0.394
D19S433 - 0.051 2.780 0.820 0.824 0.803 0.949 0.637 0.423
D1S1656 - 0.026 3.343 0.850 0.880 0.868 0.974 0.696 0.950
D21S11 - 0.039 3.234 0.845 0.855 0.838 0.961 0.686 0.383
D22S1045 - 0.126 1.760 0.716 0.720 0.679 0.874 0.453 0.259
D2S1338 - 0.033 3.459 0.855 0.870 0.856 0.967 0.706 0.040
D2S441 - 0.125 1.814 0.724 0.718 0.675 0.875 0.467 0.906
D3S1358 - 0.105 1.932 0.741 0.748 0.705 0.895 0.495 0.406
D5S818 - 0.118 1.814 0.724 0.732 0.687 0.882 0.467 0.013
D7S820 - 0.071 2.306 0.783 0.800 0.770 0.929 0.568 0.110
D8S1179 - 0.044 3.099 0.839 0.846 0.827 0.956 0.673 0.451
FGA - 0.035 3.459 0.855 0.863 0.848 0.965 0.706 0.204
PENTA-D - 0.054 2.633 0.810 0.826 0.803 0.946 0.618 0.682
PENTA-E - 0.016 6.611 0.924 0.914 0.907 0.984 0.845 0.010
TH01 - 0.087 2.324 0.785 0.775 0.739 0.913 0.571 0.691
TPOX - 0.142 1.750 0.714 0.706 0.656 0.858 0.451 0.557
vWA - 0.070 2.917 0.829 0.803 0.775 0.930 0.653 0.575

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA PENTA-D PENTA-E TH01 TPOX vWA
5 0.001 0.064 0.001
6 0.007 0.002 0.273 0.002
7 0.005 0.004 0.003 0.034 0.004 0.066 0.138 0.006
8 0.003 0.163 0.069 0.024 0.007 0.002 0.24 0.01 0.012 0.007 0.135 0.361
9 0.024 0.076 0.168 0.001 0.001 0.008 0.002 0.002 0.028 0.058 0.003 0.185 0.023 0.303 0.121
9.3 0.147
10 0.203 0.084 0.101 0.008 0.009 0.006 0.293 0.118 0.211 0.191 0.21 0.034 0.004 0.098 0.003
11 0.282 0.009 0.266 0.324 0.033 0.004 0.17 0.244 0.41 0.339 0.241 0.072 0.24 0.128 0.371
11.2 0.001
11.3 0.034
12 0.384 0.016 0.29 0.183 0.092 0.064 0.093 0.004 0.001 0.058 0.34 0.187 0.103 0.115 0.126 0.036
12.2 0.007
12.3 0.006
13 0.084 0.14 0.087 0.129 0.114 0.282 0.127 0.003 0.023 0.002 0.153 0.024 0.176 0.149 0.087 0.003 0.008
13.2 0.013
14 0.015 0.261 0.029 0.025 0.284 0.241 0.114 0.057 0.149 0.039 0.015 0.006 0.197 0.049 0.071 0.001 0.116
14.2 0.063
14.3 0.001
15 0.001 0.298 0.003 0.001 0.001 0.155 0.139 0.167 0.425 0.001 0.018 0.29 0.003 0.163 0.018 0.092 0.092
15.2 0.076
15.3 0.021
16 0.215 0.009 0.119 0.061 0.141 0.175 0.008 0.001 0.321 0.071 0.008 0.115 0.222
16.2 0.034
16.3 0.028
17 0.054 0.14 0.085 0.013 0.051 0.076 0.055 0.225 0.011 0.003 0.078 0.29
17.2 0.001
17.3 0.012 0.026
17.4 0.001
18 0.005 0.234 0.034 0.001 0.003 0.005 0.175 0.001 0.112 0.004 0.005 0.001 0.05 0.194
18.3 0.017 0.015
19 0.001 0.144 0.038 0.003 0.173 0.012 0.045 0.029 0.066
19.1 0.002
19.2 0.001
19.3 0.003 0.002
20 0.107 0.022 0.11 0.115 0.015 0.008
20.2 0.002
21 0.118 0.009 0.039 0.155 0.008 0.001
21.2 0.002
22 0.089 0.004 0.067 0.128 0.003
22.2 0.011
23 0.071 0.001 0.183 0.182 0.003
23.2 0.007
24 0.039 0.104 0.182 0.001
24.2 0.004
25 0.011 0.062 0.115
26 0.002 0.019 0.034
27 0.012 0.003 0.012
28 0.145 0.001
28.2 0.002
29 0.186
29.2 0.003
30 0.176
30.2 0.03
30.3 0.001
31 0.039
31.2 0.132
32 0.004
32.2 0.184
33.2 0.068
33.3 0.002
34.1 0.001
34.2 0.008
35.2 0.006
36.2 0.001

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