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Pakhtun, Khyber-Pakhtunkhwa province, Pakistan

Study statistics

Loci
22 Autosomal STRs
Allele type
Length-based alleles
Sample size
200
Location
Khyber-Pakhtunkhwa province, Pakistan
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Bibliographic information

Date published
Nov. 1, 2022
Title
Genetic Data of 22 Autosomal STR Loci in Khyber-Pakhtunkhwa, Balochistan and Gilgit Baltistan Population of Pakistan Using PowerPlex® Fusion System
Authors
Muhammad Shafique, Namra Sajid, Yasir Aziz, Muhammad Afzal, Muhammad Shahzad, Abida Shehzadi, Saliha Bashir, Shakeela Daud, and Ahmad Ali Shahid
Journal
Legal Medicine
Abstract

In this study we have provided forensic genetic data of 22 autosomal STRs for Pakhtun, Balochi and Balti population of Pakistan in total of 601 samples. Among these loci, Penta E was found the most discriminatory in all groups and allele 15 was observed most frequent at D22S1045 in Balti whereas in other two populations allele 8 was more common at TPOX. The combined power of discrimination, combined power of exclusion and the combined matching probability was calculated as 0.999999999999999999999999998385, 0.999999988089728 and 1.615 × 10-27 respectively. Based on population differentiation test, significant differences were observed when compared with other populations however, phylogenetic analysis revealed close genetic associations among Pakistani Populations.

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Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO - 0.115 1.613 0.690 0.735 0.687 0.885 0.413 0.207
D10S1248 - 0.084 1.754 0.715 0.778 0.743 0.916 0.452 0.146
D12S391 - 0.037 2.941 0.830 0.864 0.850 0.964 0.656 0.382
D13S317 - 0.091 1.667 0.700 0.768 0.733 0.909 0.428 0.014
D16S539 - 0.074 2.128 0.765 0.787 0.758 0.926 0.536 0.142
D18S51 - 0.036 2.083 0.760 0.867 0.853 0.964 0.527 0.000
D19S433 - 0.052 2.381 0.790 0.822 0.801 0.948 0.581 0.813
D1S1656 - 0.029 3.333 0.850 0.884 0.874 0.971 0.695 0.067
D21S11 - 0.042 3.333 0.850 0.857 0.841 0.958 0.695 0.047
D22S1045 - 0.089 1.667 0.700 0.765 0.732 0.911 0.428 0.000
D2S1338 - 0.032 2.941 0.830 0.879 0.867 0.968 0.656 0.007
D2S441 - 0.131 2.041 0.755 0.719 0.674 0.869 0.518 0.860
D3S1358 - 0.088 2.128 0.765 0.774 0.741 0.912 0.536 0.124
D5S818 - 0.101 2.041 0.755 0.750 0.710 0.899 0.518 0.681
D7S820 - 0.068 1.852 0.730 0.810 0.785 0.932 0.476 0.000
D8S1179 - 0.049 2.222 0.775 0.838 0.818 0.951 0.553 0.083
FGA - 0.038 3.704 0.865 0.869 0.855 0.962 0.725 0.001
Penta D - 0.055 2.703 0.815 0.831 0.809 0.945 0.627 0.163
Penta E - 0.020 4.000 0.875 0.908 0.900 0.980 0.745 0.247
TH01 - 0.070 1.786 0.720 0.817 0.792 0.930 0.460 0.000
TPOX - 0.159 1.449 0.655 0.678 0.623 0.841 0.362 0.786
vWA - 0.058 2.000 0.750 0.825 0.801 0.942 0.510 0.003

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA Penta D Penta E TH01 TPOX vWA
5 0.005 0.073
6 0.005 0.013 0.245
7 0.003 0.048 0.02 0.108 0.203
7.1 0.003
7.3 0.003
8 0.005 0.165 0.055 0.015 0.003 0.003 0.005 0.143 0.013 0.025 0.005 0.113 0.428
8.2 0.003
8.3 0.003
9 0.028 0.07 0.13 0.008 0.005 0.005 0.045 0.1 0.003 0.235 0.01 0.225 0.098
9.3 0.128
10 0.265 0.063 0.085 0.005 0.01 0.013 0.028 0.298 0.008 0.16 0.213 0.165 0.193 0.065 0.015 0.088
10.1 0.005
11 0.298 0.005 0.3 0.34 0.015 0.003 0.143 0.263 0.403 0.015 0.28 0.3 0.073 0.185 0.158 0.01 0.348
11.1 0.005 0.005
11.3 0.028
12 0.318 0.013 0.318 0.233 0.058 0.04 0.113 0.008 0.068 0.003 0.35 0.148 0.113 0.11 0.13 0.038 0.03
12.2 0.01
12.3 0.008
13 0.07 0.165 0.07 0.125 0.108 0.25 0.12 0.018 0.013 0.145 0.023 0.253 0.16 0.085 0.02 0.01 0.003
13.2 0.015 0.025
13.3 0.003
14 0.01 0.283 0.013 0.03 0.225 0.285 0.115 0.095 0.158 0.045 0.015 0.18 0.06 0.075 0.083
14.2 0.053
14.3 0.003 0.01
15 0.005 0.273 0.005 0.003 0.193 0.138 0.208 0.36 0.003 0.018 0.325 0.133 0.008 0.058 0.1
15.2 0.073 0.003
15.3 0.038
16 0.19 0.018 0.118 0.053 0.07 0.125 0.02 0.003 0.275 0.055 0.003 0.08 0.22
16.1 0.003
16.2 0.043
16.3 0.043
17 0.065 0.123 0.095 0.018 0.043 0.103 0.113 0.173 0.01 0.06 0.245
17.3 0.01 0.038
18 0.008 0.238 0.063 0.013 0.003 0.13 0.11 0.01 0.003 0.05 0.168
18.2 0.003
18.3 0.013 0.01
19 0.155 0.055 0.008 0.16 0.023 0.038 0.023 0.145
19.2 0.003 0.003
19.3 0.005 0.005
20 0.08 0.023 0.11 0.108 0.015 0.033
21 0.123 0.01 0.028 0.003 0.15 0.003 0.003
21.2 0.008
22 0.1 0.008 0.053 0.15
22.2 0.013
23 0.083 0.005 0.165 0.183 0.003
23.2 0.01
24 0.033 0.123 0.153
24.2 0.008
25 0.015 0.085 0.115
26 0.005 0.01 0.05
27 0.008 0.005
28 0.163 0.003 0.003
29 0.205
30 0.163
30.2 0.048
31 0.063
31.2 0.123
32 0.005
32.2 0.158
33 0.008
33.2 0.04
34.1 0.005
34.2 0.003
35.1 0.003
36.1 0.005

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