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STRidER: Entire Database

Study statistics

Loci
40 Autosomal STRs
Allele type
Unknown
Sample size
10077
Population
Unknown
Location
Entire Database
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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 4898 - - - - - - - -
D10S1248 10076 - - - - - - - -
D11S2368 500 - - - - - - - -
D12S391 10077 - - - - - - - -
D13S317 4898 - - - - - - - -
D13S325 500 - - - - - - - -
D14S1434 500 - - - - - - - -
D15S659 500 - - - - - - - -
D16S539 10076 - - - - - - - -
D17S1301 500 - - - - - - - -
D18S1364 500 - - - - - - - -
D18S51 10074 - - - - - - - -
D19S253 500 - - - - - - - -
D19S433 10076 - - - - - - - -
D1S1656 10077 - - - - - - - -
D20S482 500 - - - - - - - -
D21S11 10076 - - - - - - - -
D21S2055 500 - - - - - - - -
D22GATA198B05 500 - - - - - - - -
D22S1045 10076 - - - - - - - -
D2S1338 10073 - - - - - - - -
D2S441 10077 - - - - - - - -
D3S1358 10075 - - - - - - - -
D3S1744 500 - - - - - - - -
D4S2366 500 - - - - - - - -
D5S2800 500 - - - - - - - -
D5S818 4898 - - - - - - - -
D6S474 500 - - - - - - - -
D7S3048 500 - - - - - - - -
D7S820 4898 - - - - - - - -
D8S1132 500 - - - - - - - -
D8S1179 10076 - - - - - - - -
D9S1122 500 - - - - - - - -
FGA 10073 - - - - - - - -
Penta D 1198 - - - - - - - -
Penta E 1198 - - - - - - - -
SE33 7921 - - - - - - - -
TH01 10076 - - - - - - - -
TPOX 4898 - - - - - - - -
VWA 10070 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D11S2368 D12S391 D13S317 D13S325 D14S1434 D15S659 D16S539 D17S1301 D18S1364 D18S51 D19S253 D19S433 D1S1656 D20S482 D21S11 D21S2055 D22GATA198B05 D22S1045 D2S1338 D2S441 D3S1358 D3S1744 D4S2366 D5S2800 D5S818 D6S474 D7S3048 D7S820 D8S1132 D8S1179 D9S1122 FGA Penta D Penta E SE33 TH01 TPOX VWA
1 0.000297737 0.0000496229 0.0000992457 0.00133968 0.000297826 0.0000496278 0.0000496229 0.000198551
2.2 0.000417362
5 0.0838898 0.000744343
6 0.00040833 0.001 0.004 0.000204165 0.000834725 0.000417362 0.194869 0.00040833
6.3 0.000102082 0.00018937
7 0.0034708 0.00224581 0.003 0.222 0.0175582 0.0116374 0.001 0.00417362 0.154424 0.203503 0.000714577
7.3 0.0000631233 0.0000496229
8 0.0023479 0.244998 0.0148372 0.018 0.000744269 0.0017354 0.169865 0.00947797 0.0158598 0.0116861 0.0000631233 0.099345 0.56472
8.3 0.000396983
9 0.0279706 0.000148869 0.112495 0.001 0.006 0.134676 0.001 0.00054596 0.009 0.00163755 0.000396944 0.01 0.00129007 0.299 0.0479788 0.106064 0.00888249 0.008 0.208264 0.0104341 0.000126247 0.235957 0.115557
9.1 0.00287784 0.00153124
9.2 0.0000631233
9.3 0.000102082 0.237098
10 0.223765 0.000198491 0.105043 0.29 0.037 0.0769154 0.042 0.00660115 0.018 0.000496229 0.00262975 0.004 0.000248114 0.195098 0.107 0.16619 0.001 0.209882 0.0969135 0.054 0.102254 0.0838898 0.000126247 0.027243 0.0480808
10.1 0.000204165 0.000297708 0.000204165
10.2 0.0000496229
10.3 0.0000992359 0.000102082 0.0000496229
11 0.311249 0.00302699 0.263577 0.036 0.222 0.295504 0.292 0.001 0.00928132 0.147 0.00367209 0.0799345 0.007 0.148869 0.322467 0.000843672 0.172 0.306962 0.303389 0.0931421 0.237 0.148998 0.128548 0.000441863 0.000645097 0.246835 0.0000496524
11.1 0.0000496179 0.000204165
11.2 0.0000992457 0.001 0.00018937
11.3 0.0922398 0.000102082
12 0.353205 0.0334458 0.1912 0.018 0.163 0.292924 0.449 0.045 0.111326 0.353 0.0774117 0.101022 0.039 0.004 0.00952759 0.0670338 0.000645161 0.001 0.243 0.287771 0.163128 0.130409 0.405 0.225793 0.204508 0.00347178 0.0000992457 0.0227644 0.000148957
12.1 0.0000496229 0.000396983 0.0000496229 0.0000631233
12.2 0.0000496229 0.00302699 0.000441863
12.3 0.00203434 0.000102082 0.0000631233
13 0.068089 0.291931 0.0589016 0.261 0.059 0.159041 0.188 0.247 0.133661 0.16 0.239629 0.0779002 0.222 0.00565701 0.0267441 0.0030273 0.008 0.106 0.021 0.158534 0.002 0.0277664 0.279277 0.256 0.201169 0.107679 0.00694357 0.000612495 0.00183714
13.1 0.001
13.2 0.0217348 0.00132559
13.3 0.0000992359 0.000297708 0.0000631233
14 0.00877909 0.287664 0.001 0.00024809 0.0201102 0.384 0.037 0.0247122 0.023 0.142 0.171332 0.061 0.319174 0.0904535 0.477 0.01 0.046447 0.000248188 0.250968 0.0889826 0.117 0.066 0.238 0.0109228 0.345 0.00541037 0.201717 0.031 0.0751252 0.0434057 0.018937 0.000306247 0.149206
14.1 0.0000496327
14.2 0.0427749 0.00157808
14.3 0.00218319 0.00018937
15 0.00112291 0.218291 0.002 0.0316562 0.00081666 0.006 0.207 0.00119095 0.005 0.185 0.17426 0.007 0.138597 0.177434 0.186 0.011 0.361999 0.000446739 0.0346333 0.267444 0.079 0.005 0.003 0.0023479 0.244 0.000204165 0.003 0.132046 0.007 0.015025 0.0505008 0.0300467 0.0804369
15.2 0.0779575 0.00100997
15.3 0.0451027 0.0000496179 0.0000496229 0.000631233
16 0.130012 0.016 0.0215838 0.004 0.004 0.18 0.0000496229 0.126 0.144779 0.001 0.0406411 0.146323 0.052 0.131 0.292576 0.0361858 0.00302669 0.277717 0.133 0.002 0.001 0.214 0.003 0.016 0.0409389 0.001 0.00148913 0.00208681 0.0417362 0.0403358 0.185402
16.1 0.0000992359 0.082 0.000252493
16.2 0.0000496327 0.0239182 0.000504987
16.3 0.0000992359 0.0392974 0.00138871
17 0.0321556 0.048 0.0991366 0.012 0.061 0.043 0.100308 0.00312624 0.0599881 0.003 0.188 0.120981 0.188673 0.0000496179 0.21866 0.34 0.239 0.143 0.068 0.138 0.00610361 0.0011913 0.0392321 0.0671001 0.268173
17.1 0.00024809 0.013 0.0000631233
17.2 0.00372171 0.00056811
17.3 0.0138434 0.112732 0.00075748
18 0.00258039 0.143 0.187159 0.045 0.021 0.143 0.0625869 0.000198491 0.00739307 0.099 0.0121576 0.082051 0.130323 0.167 0.28 0.039 0.091 0.211 0.000992457 0.0153877 0.0179466 0.0743593 0.210377
18.1 0.013 0.0000631233
18.2 0.00153831 0.000883727
18.3 0.0137938 0.0458966 0.000694357
19 0.000248114 0.241 0.138087 0.167 0.003 0.062 0.0403018 0.000744269 0.244 0.00129019 0.138836 0.011464 0.096 0.006 0.012 0.061 0.2 0.0714782 0.0108514 0.0744855 0.0870407
19.1 0.108 0.0000631233
19.2 0.0000992359 0.000148913 0.00220932
19.3 0.00754193 0.0082862 0.0000631233
20 0.266 0.135556 0.308 0.006 0.021888 0.0000496179 0.153 0.000198491 0.132681 0.000843672 0.045 0.025 0.075 0.124 0.114663 0.0066778 0.0536548 0.0160874
20.1 0.01 0.0000631233
20.2 0.0000496179 0.00104239 0.00770105
20.3 0.00119083 0.000446561
21 0.206 0.117694 0.231 0.0119119 0.11 0.0348953 0.012 0.106 0.105 0.165293 0.00208681 0.031751 0.00109235
21.1 0.000315617
21.2 0.00645289 0.0143921
21.3 0.000297708 0.0000496376
22 0.059 0.105934 0.141 0.0077427 0.044 0.0351435 0.002 0.003 0.086 0.106 0.186687 0.00208681 0.0104154 0.000148957
22.1 0.0000496179 0.0000496327 0.0000631233
22.2 0.0109699 0.0258174
22.3 0.000148854
23 0.016 0.0796864 0.071 0.00168751 0.001 0.005 0.129802 0.165 0.186 0.069 0.155217 0.00227244
23.2 0.00694927 0.0390102
24 0.002 0.028828 0.017 0.00114155 0.026 0.114961 0.019 0.181 0.023 0.133029 0.000504987
24.1 0.0000496376
24.2 0.000396983 0.0054105 0.0380003
24.3 0.0000631233
25 0.0132976 0.001 0.000397062 0.00034736 0.131 0.0876104 0.098 0.004 0.0810086 0.00037874
25.2 0.00034736 0.00243224 0.043997
26 0.00312593 0.0000992654 0.00124057 0.121 0.0160826 0.037 0.0321156 0.000252493
26.1 0.0000631233
26.2 0.0000992457 0.000546014 0.0594622
26.3 0.002 0.00018937
27 0.000793887 0.0221814 0.014 0.00188623 0.006 0.00570833 0.0000631233
27.2 0.000148913 0.0771998
27.3 0.001 0.00018937
28 0.122817 0.012 0.000198551 0.001 0.0015884 0.000504987
28.1 0.0000496229
28.2 0.00034736 0.0000496376 0.081871
28.3 0.0000496229 0.0000631233
29 0.224246 0.056 0.000347464 0.000441863
29.2 0.000893212 0.0666583
29.3 0.000198491 0.000126247
30 0.242011 0.032 0.001 0.0000496376 0.000252493
30.1 0.0000496229 0.0000631233
30.2 0.0423779 0.0530236
30.3 0.000297737
31 0.0712584 0.041 0.000315617
31.1 0.000198551
31.2 0.087634 0.0302361
31.3 0.0000496229
32 0.0180131 0.102 0.000441863
32.1 0.0000496376
32.2 0.117705 0.0140134
32.3 0.000126247
33 0.00178642 0.124 0.00277743
33.1 0.000198491
33.2 0.0396487 0.0000496376 0.00637546
34 0.000198491 0.07 0.0018937
34.2 0.00481342 0.0029668
35 0.0000496229 0.034 0.00094685
35.1 0.0000496229
35.2 0.000645097 0.000504987
36 0.008 0.000441863
36.2 0.00018937
37 0.002 0.000126247
99 0.0000992359 0.0000992457

Locus histograms

CSF1PO

D10S1248

D11S2368

D12S391

D13S317

D13S325

D14S1434

D15S659

D16S539

D17S1301

D18S1364

D18S51

D19S253

D19S433

D1S1656

D20S482

D21S11

D21S2055

D22GATA198B05

D22S1045

D2S1338

D2S441

D3S1358

D3S1744

D4S2366

D5S2800

D5S818

D6S474

D7S3048

D7S820

D8S1132

D8S1179

D9S1122

FGA

Penta D

Penta E

SE33

TH01

TPOX

VWA