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STRidER: Slovenia

Study statistics

Loci
21 Autosomal STRs
Allele type
Unknown
Sample size
907
Population
Unknown

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Bibliographic information

Date published
2016
Title
Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on Quality Control of Autosomal Short Tandem Repeat Allele Frequency Databasing (STRidER)
Authors
Martin Bodner, Ingo Bastisch, John M. Butler, Rolf Fimmers, Peter Gill, Leonor Gusmão, Niels Morling, Christopher Phillips, Mechthild Prinz, Peter M. Schneider, and Walther Parson
Journal
Forensic Science International: Genetics
Abstract

The statistical evaluation of autosomal Short Tandem Repeat (STR) genotypes is based on allele frequencies. These are empirically determined from sets of randomly selected human samples, compiled into STR databases that have been established in the course of population genetic studies. There is currently no agreed procedure of performing quality control of STR allele frequency databases, and the reliability and accuracy of the data are largely based on the responsibility of the individual contributing research groups. It has been demonstrated with databases of haploid markers (EMPOP for mitochondrial mtDNA, and YHRD for Y-chromosomal loci) that centralized quality control and data curation is essential to minimize error. The concepts employed for quality control involve software-aided likelihood-of-genotype, phylogenetic, and population genetic checks that allow the researchers to compare novel data to established datasets and, thus, maintain the high quality required in forensic genetics.

Here, we present STRidER (http://strider.online), a publicly available, centrally curated online allele frequency database and quality control platform for autosomal STRs. STRidER expands on the previously established ENFSI DNA WG STRbASE and applies standard concepts established for haploid and autosomal markers as well as novel tools to reduce error and increase the quality of autosomal STR data. The platform constitutes a significant improvement and innovation for the scientific community, offering autosomal STR data quality control and reliable STR genotype estimates.

Forensic parameters

Forensic parameters for each locus as reported by the authors.
Locus # MP PI Hobs Hexp PIC PD PE HWE
CSF1PO 700 - - - - - - - -
D10S1248 907 - - - - - - - -
D12S391 907 - - - - - - - -
D13S317 700 - - - - - - - -
D16S539 907 - - - - - - - -
D18S51 907 - - - - - - - -
D19S433 907 - - - - - - - -
D1S1656 907 - - - - - - - -
D21S11 907 - - - - - - - -
D22S1045 907 - - - - - - - -
D2S1338 906 - - - - - - - -
D2S441 907 - - - - - - - -
D3S1358 907 - - - - - - - -
D5S818 700 - - - - - - - -
D7S820 700 - - - - - - - -
D8S1179 907 - - - - - - - -
FGA 907 - - - - - - - -
SE33 700 - - - - - - - -
TH01 907 - - - - - - - -
TPOX 700 - - - - - - - -
VWA 907 - - - - - - - -

Allele frequencies

CSF1PO D10S1248 D12S391 D13S317 D16S539 D18S51 D19S433 D1S1656 D21S11 D22S1045 D2S1338 D2S441 D3S1358 D5S818 D7S820 D8S1179 FGA SE33 TH01 TPOX VWA
1 0.000551268 0.000551876
5 0.000551268
6 0.000714286 0.245314 0.00214286
6.3 0.000714286
7 0.00142857 0.0214286 0.134509
8 0.00285714 0.127857 0.014333 0.00110254 0.00214286 0.163571 0.0126792 0.098677 0.557857
9 0.0457143 0.0935714 0.118523 0.000551268 0.000551268 0.0528571 0.173571 0.00771775 0.194598 0.102857
9.2 0.000714286
9.3 0.318082
10 0.254286 0.00110254 0.0585714 0.0584344 0.0137817 0.000551268 0.00385888 0.206725 0.0864286 0.272143 0.0573319 0.00826902 0.0714286
11 0.307857 0.00330761 0.355 0.27839 0.00771775 0.00551268 0.0931643 0.130099 0.307056 0.308571 0.197857 0.0810364 0.00142857 0.238571
11.3 0.0633958
12 0.322857 0.0248071 0.24 0.329658 0.120728 0.106395 0.143881 0.0203969 0.0457552 0.000551268 0.385 0.137857 0.15215 0.00214286 0.0264286 0.000551268
12.2 0.00220507 0.000714286
12.3 0.0016538
13 0.0564286 0.245865 0.0935714 0.172547 0.112459 0.238699 0.070011 0.00385888 0.0292172 0.00110254 0.154286 0.0278571 0.338479 0.00857143 0.000714286 0.00496141
13.2 0.0203969 0.000714286
14 0.00714286 0.316428 0.0307143 0.0242558 0.168137 0.34344 0.0898567 0.0567806 0.306505 0.0931643 0.00857143 0.005 0.213892 0.0271429 0.107497
14.2 0.0176406 0.00357143
14.3 0.00330761
15 0.00285714 0.210033 0.0402426 0.000714286 0.00385888 0.138368 0.147189 0.125689 0.359427 0.00165563 0.0347299 0.248071 0.000714286 0.109702 0.0392857 0.106395
15.2 0.0336273 0.00357143
15.3 0.0523705 0.00142857
16 0.164829 0.0330761 0.16097 0.0490628 0.123484 0.332966 0.0568433 0.00330761 0.257993 0.0248071 0.00110254 0.0492857 0.199008
16.2 0.0220507 0.00142857
16.3 0.000551268 0.045204 0.000714286
17 0.0319735 0.0975744 0.110254 0.00220507 0.0512679 0.0871003 0.242274 0.210584 0.00220507 0.00220507 0.0728571 0.272878
17.1 0.000714286
17.2 0.00661521 0.000714286
17.3 0.014333 0.13065 0.00142857
18 0.0016538 0.189085 0.0931643 0.00330761 0.00826902 0.0783664 0.168688 0.0148842 0.0785714 0.232084
18.2 0.00441014
18.3 0.0104741 0.0496141 0.00142857
19 0.106395 0.0286659 0.00110254 0.0921634 0.0187431 0.0859978 0.0664286 0.0584344
19.2 0.00142857
19.3 0.00882029 0.0137817
20 0.121279 0.0214994 0.134106 0.00110254 0.12183 0.0428571 0.0148842
20.2 0.00857143
20.3 0.00275634
21 0.114664 0.0121279 0.0237307 0.167034 0.0307143 0.00330761
21.2 0.00220507 0.0135714
21.3 0.000551268
22 0.12624 0.00826902 0.0342163 0.205623 0.01
22.2 0.0159868 0.0271429
23 0.0981257 0.0016538 0.102649 0.140022 0.00285714
23.2 0.00992282 0.0457143
24 0.022602 0.00110254 0.108168 0.124587
24.1 0.000551268
24.2 0.000551268 0.0407143
25 0.0115766 0.000551268 0.107616 0.0722161
25.2 0.000551268 0.0435714
26 0.0016538 0.00330761 0.0137969 0.0286659
26.2 0.0578571
27 0.0242558 0.00331126 0.00496141 0.000714286
27.2 0.065
28 0.159868 0.000551876 0.0016538
28.2 0.0764286
29 0.198456 0.000714286
29.2 0.000551268 0.0564286
30 0.226571
30.2 0.047409 0.0457143
31 0.0815877
31.2 0.0826902 0.0357143
32 0.0159868
32.2 0.120176 0.0121429
33 0.0016538 0.00214286
33.2 0.0341786 0.00428571
34 0.00357143
34.2 0.00275634 0.00571429
35 0.000714286
35.2 0.000714286
36.2 0.000714286
37 0.000714286

Locus histograms

CSF1PO

D10S1248

D12S391

D13S317

D16S539

D18S51

D19S433

D1S1656

D21S11

D22S1045

D2S1338

D2S441

D3S1358

D5S818

D7S820

D8S1179

FGA

SE33

TH01

TPOX

VWA